NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By


 
Result: 1 - 3 of 3 rows are displayed

Reaction List for pathway Ras (Pathway Number 63) in Accession MAPK_MKP1_oscillation (Accession Number 9)

Entries are grouped according to Pathway Number and they are alternately color coded using  and  color.
Further ordering can be done to the table header.  indicates that ordering is done according to ascending or descending order.
Keq is calculated only for first order reactions.
Kd is calculated only for second order reactions. [nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules]
  Reaction
Name
Pathway Name / 
Pathway No.
KfKbKdtauReagents
1 dephosph-GEFRas

Pathway No. 63
1
(s^-1)
0
(s^-1)
--  Substrate:
 GEF*

 Products:
 inact-GEF
2 
  • Ras-intrinsic-GT
    Pase
  • Ras

    Pathway No. 63
    0.0001
    (s^-1)
    0
    (s^-1)
    --  Substrate:
     GTP-Ras

     Products:
     GDP-Ras
      This is extremely slow (1e-4), but it is significant as so little GAP actually gets complexed with it that the total GTP turnover rises only by 2-3 X (see Gibbs et al, JBC 265(33) 20437-20422) and Eccleston et al JBC 268(36) 27012-27019 kf = 1e-4
    3 dephosph-GAPRas

    Pathway No. 63
    0.1
    (s^-1)
    0
    (s^-1)
    --  Substrate:
     GAP*

     Products:
     GAP
      Assume a reasonably good rate for dephosphorylating it, 1/sec

     
    Result: 1 - 3 of 3 rows are displayed



    Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.