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Accession Type:
Network
fig3_CaMKII
Shared_Object_
fig3_CaMKII
CaMKII
CaM
PP1
PP2B
PKA
AC

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Accession information for fig3_CaMKII (Accession Number 2)

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Accession Basic Parameters

Name fig3_CaMKII
Accession Type Network
Transcriber Upinder S. Bhalla, NCBS
Developer Upinder S. Bhalla, NCBS
Entry Date (YYYY-MM-DD) 2001-11-07
Species Generic mammalian
Tissue Neuronal
Cell Compartment Synapse
Source Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )
Methodology Quantitative match to experiments, Qualitative
Model Implementation Exact GENESIS implementation
Model Validation Approximates orginal data, Quantitatively predicts new data
Notes This is the model file for figure 3 from Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It is a model of the Ca activation of CaMKII and other CaM-activated enzymes. It includes the regulatory phosphatases PP1 and PP2B (Calcineurin) acting on CaMKII and also includes CaM-activated adenylyl cyclase and PKA in the synapse.
Demonstration script files for generating the figures in the paper, including figure 3, are available here.

Conversion formats

FormatFile
Native Format (GENESIS format)    acc2.g   
GENESIS Format (Annotated version)    Anno_acc2.g   



Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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