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Accession Type:
Network
fig3_CaMKII
Shared_Object_
fig3_CaMKII
CaMKII
CaM
PP1
PP2B
 Molecule
 Reaction
PKA
AC

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Parameters for PP2B (Pathway Number 16)

Pathway Layout

Pathway Basic Parameters

Pathway NamePP2B
Pathway Entry Number 16
Accession Number 2
Accession Name fig3_CaMKII
Species Generic mammalian
Tissue Neuronal
CellCompartmentSynapse
Related Pathways 29, 83, 205, 219, 238, 248, 261, 267, 276, 285, 325, 342, 360
Notes  This is the model file for figure 3 from Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It is a model of the Ca activation of CaMKII and other CaM-activated enzymes. It includes the regulatory phosphatases PP1 and PP2B (Calcineurin) acting on CaMKII and also includes CaM-activated adenylyl cyclase and PKA in the synapse.
Demonstration script files for generating the figures in the paper, including figure 3, are available here.

Statistics

Enzyme sites
5
0
5

Conversion format

This pathway is part of accession 2 and is completely specified in the file acc2.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc2.g   
GENESIS Format (Annotated version)    Anno_acc2.g   


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Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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