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Molecule Parameter List for CaM-GEF

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

*CaM-GEF* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	25	0	25	0	0	24	49

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13	82	Network	Shared_Object_Ajay_Bhalla_2007_ReacDiff1_1e-13, PKC, MAPK, Ras, CaM, PKM, chain, kinetics, PKC, MAPK, Ras, CaM, PKM, kinetics[1], PKC, MAPK, Ras, CaM, PKM, kinetics[2], PKC, MAPK, Ras, CaM, PKM, kinetics[3], PKC, MAPK, Ras, CaM, PKM, kinetics[4], PKC, MAPK, Ras, CaM, PKM, kinetics[5], PKC, MAPK, Ras, kinetics[6], CaM, PKM, PKC, MAPK, Ras, CaM, PKM, kinetics[7], PKC, MAPK, Ras, CaM, PKM, kinetics[8], PKC, MAPK, Ras, CaM, PKM, kinetics[9], PKC, MAPK, Ras, CaM, PKM, kinetics[10], PKC, MAPK, Ras, CaM, PKM, kinetics[11], PKC, MAPK, Ras, CaM, PKM, kinetics[12], PKC, MAPK, Ras, CaM, PKM, kinetics[13], PKC, MAPK, Ras, CaM, PKM, kinetics[14], PKC, MAPK, Ras, CaM, PKM, kinetics[15], PKC, MAPK, Ras, CaM, PKM, kinetics[16], PKC, MAPK, Ras, CaM, PKM, kinetics[17], PKC, MAPK, Ras, CaM, PKM, kinetics[18], PKC, MAPK, Ras, CaM, PKM, kinetics[19], PKC, MAPK, Ras, CaM, PKM, kinetics[20], PKC, MAPK, Ras, CaM, PKM, kinetics[21], PKC, MAPK, Ras, CaM, PKM, kinetics[22], PKC, MAPK, Ras, CaM, PKM, kinetics[23], PKC, MAPK, Ras, CaM, PKM
This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec. The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper. pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H. pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.

CaM-GEF acting as a Molecule in Ajay_Bhalla_2007_ReacDiff1_1e-13 Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 529	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 536	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 542	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 548	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 554	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 560	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 566	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 572	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 578	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 584	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 590	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 596	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 602	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 608	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 614	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 620	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 626	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 632	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 638	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 644	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 650	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 656	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 662	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 668	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995
CaM-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 674	0	1.5	No
See Farnsworth et al Nature 376 524-527 1995

CaM-GEF acting as an Enzyme in Ajay_Bhalla_2007_ReacDiff1_1e-13 Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 529	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
2	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 536	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
3	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 542	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
4	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 548	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
5	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 554	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
6	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 560	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
7	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 566	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
8	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 572	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
9	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 578	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
10	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 584	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
11	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 590	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
12	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 596	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
13	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 602	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
14	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 608	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
15	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 614	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
16	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 620	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
17	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 626	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
18	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 632	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
19	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 638	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
20	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 644	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
21	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 650	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
22	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 656	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
23	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 662	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
24	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 668	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.
25	CaM-GEF / CaM-GEF-act-ras	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 674	0.505057	0.2	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras
	Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input.

CaM-GEF acting as a Substrate in a reaction in Ajay_Bhalla_2007_ReacDiff1_1e-13 Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
2	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
3	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
4	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
5	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
6	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
7	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
8	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
9	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
10	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
11	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
12	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
13	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
14	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
15	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
16	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
17	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
18	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
19	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
20	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
21	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
22	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
23	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
24	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF

CaM-GEF acting as a Product in a reaction in Ajay_Bhalla_2007_ReacDiff1_1e-13 Network

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 529	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
2	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
3	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 536	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
4	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
5	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 542	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
6	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
7	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 548	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
8	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
9	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 554	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
10	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
11	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 560	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
12	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
13	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 566	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
14	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
15	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 572	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
16	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
17	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 578	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
18	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
19	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 584	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
20	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
21	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 590	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
22	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
23	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 596	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
24	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
25	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 602	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
26	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
27	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 608	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
28	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
29	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 614	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
30	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
31	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 620	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
32	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
33	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 626	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
34	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
35	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 632	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
36	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
37	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 638	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
38	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
39	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 644	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
40	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
41	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 650	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
42	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
43	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 656	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
44	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
45	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 662	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
46	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
47	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 668	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
48	diff	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate CaM-GEF Product CaM-GEF
49	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82	Ras Pathway No. : 674	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995

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