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Molecule Parameter List for IP1(3)

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
IP1(3) participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000110

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • NonOsc_Ca_
    IP3metabolism
  • 23Network
    MIPP CaMKII CaM 
    PKC IP3-3K CaRegulation 
    Gq PLCbeta 134_dephos 
    145_dephos IP4-system IHP-system 
    1345_dephos 
    This network models detailed metabolism of Ins(145)P3, integrated with GPCR mediated PLCbeta activation and Ca release by the InsP3 receptor in the neuron. The calcium response is non-oscillatory. Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316.

    IP1(3) acting as a Molecule in  
    NonOsc_Ca_IP3metabolism Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    IP1(3)
  • NonOsc_Ca_
    IP3metabolism

    Accession No. : 23
  • 134_dephos
    Pathway No. : 113
    01000No
    Inositol (3)monophsophate Conc equals 11% of Ins(1)P1 conc as per Ackerman et al, Biochem J 242(2); 1987: 517

    IP1(3) acting as a Product of an Enzyme in  
    NonOsc_Ca_IP3metabolism Network
    Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    IP_4pase  /
    ip2_4pase
  • NonOsc_Ca_
    IP3metabolism

    Accession No. : 23
  • 134_dephos
    Pathway No. : 113
    22.9995554explicit E-S complexSubstrate
    IP2(34)

    Product
    IP1(3)
    Ins(34)P2 4-phosphatase activity of InsP 4-phosphatase from Norris et al, JBC 269; 1994

    IP1(3) acting as a Substrate in a reaction in  
    NonOsc_Ca_IP3metabolism Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    IP1(3)_deg
  • NonOsc_Ca_
    IP3metabolism

    Accession No. : 23
  • 134_dephos
    Pathway No. : 113
    35
    (s^-1)
    0
    (s^-1)
    --Substrate
    IP1(3)

    Product
    inositol
    rate based on levels of Ins(3)P1



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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