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Molecule List for pathway Shared_Object_AMPAR_CaMKII_strong_coupling (Pathway Number 271) in Accession AMPAR_CaMKII_strong_coupling (Accession Number 64)

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The entries are grouped according to Pathway Number and are alternately color coded using

and

color.

	Name	Accession Type	Initial Conc. (uM)	Volume (fL)	Buffered	Sum Total Of
1	tot_mem_GluR12	Network	0	0	No	Ser845 Ser845-P Ser845-PP
2	tot_I_GluR12	Network	0	0	No	I_845 I_845-P I_845_PP
3	tot_CaMKII_PSD	Network	2	0	No	actCaMKII-PSD CaMKII-PSD CaMKII-thr305-PS D
4	tot_CaMKII_cyt	Network	22	0	No	CaMKII-CaM CaMKII-thr286-C aM CaMKII-thr286 CaMKII** CaMK-thr305 CaMKII basal_CaMKII_ cyt
5	total_Int	Network	0	0	No	tot_I_GluR12 GluR23_I
6	tot-CaM-CaMKII-P SD	Network	0	0	No	CaMKII-thr286-Ca M-PSD CaMKII-CaM-PSD
7	tot-auto-PSD	Network	2	0	No	CaMKII-thr286-PS D CaMKII***-PSD basal_CaMKII_ PSD
8	temp-PIP2	Network	2.5	0	Yes	-
	This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
9	Ser845-PP	Network	0	0	No	A845_B845 A831845_B845* A845_B831845* A835845_ B835845
10	Ser845-P	Network	0	0	No	A845_B A831845_B A845_B831* A831845_B831* A_B845* A831_B845 A_B831845 A831_B831845*
11	Ser845	Network	0	0	No	A_B A831_B A_B831 A831_B831
12	Ser831-PP	Network	0	0	No	A835845_ B835845 A831_B831845* A831845_B831* A831_B831
13	Ser831-P	Network	0	0	No	A831845_B845* A845_B831845* A831_B845 A_B831845 A831845_B A845_B831 A831_B A_B831
14	Ser831	Network	0	0	No	A845_B845 A_B845* A845*_B A_B
15	PP2A	Network	0.1111	0	No	-
16	PP1-active_PSD	Network	8	0	No	-
	Cohen et al Meth Enz 159 390-408 is main source of info conc = 1.8 uM
17	PP1-active	Network	1.8	0	No	-
	Cohen et al Meth Enz 159 390-408 is main source of info conc = 1.8 uM
18	PKC-control	Network	0.1	0	Yes	-
19	PKC-active	Network	0.1	0	No	-
20	PKA-active	Network	0	0	No	-

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