| | Molecule Name/
Site Name | Km (uM) | kcat (1/s) | Ratio
(k2/k3) | Enzyme Type | Substrate | Product |
| 1 |
Enzyme Activity:
internal-PKA-act
Enzyme Molecule:
PKA-active | 3.74995 | 6 | 4 | explicit E-S complex | IR
| IR*
|
| | Note that Km is halved from the main model, from 7.5 to 3.75. This is because here we lump two subunits into one, thus double the effective substrate conc that the enzyme must deal with. We thank an anonymous reviewer for pointing this out. |
| 2 |
Enzyme Activity:
internal-PKA-act
[1]
Enzyme Molecule:
PKA-active | 3.74995 | 6 | 4 | explicit E-S complex | IR*
| IR**
|
| | Note that Km is halved from the detailed model, as the reaction represents enzyme activity on 2 subunits. |
| 3 |
Enzyme Activity:
memb-PKA-act
Enzyme Molecule:
PKA-active | 3.74995 | 6 | 4 | explicit E-S complex | MR
| MR*
|
| | Note halving of Km. See notes for internal-PKA-act enzymatic step. |
| 4 |
Enzyme Activity:
memb-PKA-act[1]
Enzyme Molecule:
PKA-active | 3.74995 | 6 | 4 | explicit E-S complex | MR*
| MR**
|
| | Note halving of Km. See notes for internal-PKA-act enzyme step. |
