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Accession Type:
Network
CaMKII_model3
Shared_Object_
CaMKII_model3
CaMKII
CaM
PP1
PP2B
PP1_PSD
 Molecule
 Reaction
AC
PKA

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Molecule List for pathway PP1_PSD (Pathway Number 268)

 Name Initial Conc. (uM) Volume (fL) Buffered
1I140.01No
    I1 is a 'mixed' inhibitor, but at high enz concs it looks like a non-compet inhibitor (Foulkes et al Eur J Biochem 132 309-313 9183). We treat it as non-compet, so it just turns the enz off without interacting with the binding site. Cohen et al ann rev bioch refer to results where conc is 1.5 to 1.8 uM. In order to get complete inhib of PP1, which is at 1.8 uM, we need >= 1.8 uM.
2I1*00.01No
    Dephosph is mainly by PP2B
3PP1-I100.01No
   
4PP1-I1*00.01No
   


Pathway Details  Molecule List  Enzyme List   Reaction List  


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