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Molecule Parameter List for tot_PP1 | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
| tot_PP1 participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction | | No. of occurrences | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | | fig3_CaMKII | 2 | Network |
Shared_Object_fig3_CaMKII, CaMKII, CaM,
PP1, PP2B, PKA,
AC | This is the model file for figure 3 from Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It is a model of the Ca activation of CaMKII and other CaM-activated enzymes. It includes the regulatory phosphatases PP1 and PP2B (Calcineurin) acting on CaMKII and also includes CaM-activated adenylyl cyclase and PKA in the synapse.
Demonstration script files for generating the figures in the paper, including figure 3, are available here. |
tot_PP1 acting as a Molecule in fig3_CaMKII Network
| Name | Accession Name | Pathway Name | Initial Conc.
(uM) | Volume
(fL) | Buffered | | tot_PP1 | fig3_CaMKII
Accession No. : 2 | Shared_Object_
fig3_CaMKII
Pathway No. : 12 | 0 | 1000 | No | tot_PP1 has inputs from Deph-thr286, PP1-active, Deph-thr305, Deph-thr286c, Deph-thr286b,Deph-thr305.
except PP1-active all other inputs are enzyme-substrate complex which is not currently supported by doqcs.
But can be accessed from GENESIS file.
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tot_PP1 acting as a Summed Molecule in fig3_CaMKII Network
| Accession Name | Pathway Name | Target | Input | fig3_CaMKII
Accession No. : 2 | Shared_Object_
fig3_CaMKII
Pathway No. : 12 | tot_PP1 | PP1-active
| tot_PP1 has inputs from Deph-thr286, PP1-active, Deph-thr305, Deph-thr286c, Deph-thr286b,Deph-thr305.
except PP1-active all other inputs are enzyme-substrate complex which is not currently supported by doqcs.
But can be accessed from GENESIS file.
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| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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