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Molecule Parameter List for IP1(4) | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | Statistics | Accession and Pathway Details | |
Accession Name | Accession No. | Accession Type | Pathway Link | NonOsc_Ca_ IP3metabolism | 23 | Network | MIPP, CaMKII, CaM, PKC, IP3-3K, CaRegulation, Gq, PLCbeta, 134_dephos, 145_dephos, IP4-system, IHP-system, 1345_dephos | This network models detailed metabolism of Ins(145)P3, integrated with GPCR mediated PLCbeta activation and Ca release by the InsP3 receptor in the neuron. The calcium response is non-oscillatory. Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. |
IP1(4) acting as a Molecule in NonOsc_Ca_IP3metabolism Network
Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | IP1(4) | NonOsc_Ca_ IP3metabolism Accession No. : 23 | 145_dephos Pathway No. : 114 | 0 | 1000 | No | Inositol 4-monophosphate |
IP1(4) acting as a Substrate for an Enzyme in NonOsc_Ca_IP3metabolism Network
Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | IP1_pase / ip1_4pase | NonOsc_Ca_ IP3metabolism Accession No. : 23 | 145_dephos Pathway No. : 114 | 190 | 39.33 | 4 | explicit E-S complex | Substrate IP1(4)
Product inositol
| Ins(4)P1 4-phsophatase from Gee et al, BiochemJ 249; 1988 |
IP1(4) acting as a Product of an Enzyme in NonOsc_Ca_IP3metabolism Network
Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | IP_1pase / ip2_1pase | NonOsc_Ca_ IP3metabolism Accession No. : 23 | 145_dephos Pathway No. : 114 | 5.00005 | 2 | 4 | explicit E-S complex | Substrate IP2(14)
Product IP1(4)
| from Inhorn and Majerus, JBC 1987 Vmax reduced from 5.625 to 2 to maintain levels of IP2(14) |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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