|
Enter a Search String | | Special character and space not allowed in the query term.
Search string should be at least 2 characters long. |
Molecule Parameter List for PP-IP5-K | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | Osc_Ca_
IP3metabolism | 24 | Network |
MIPP, CaMKII, CaM,
PKC, IP3-3K, Gq,
PLCbeta, 134_dephos, 145_dephos,
IP4-system, IHP-system, 1345_dephos,
CaRegulation, Othmer-Tang-model | | This network models an oscillatory calcium response to GPCR mediated PLCbeta activation, alongwith detailed InsP3 metabolism in the neuron. It differs from the NonOsc_Ca_IP3metabolism network in the CaRegulation module and in InsP3 receptor kinetics. Details of InsP3 receptor kinetics have been adapted from the Othmer-Tang model for oscillatory Ca dynamics. Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. |
PP-IP5-K acting as a Molecule in Osc_Ca_IP3metabolism Network
| Name | Accession Name | Pathway Name | Initial Conc.
(uM) | Volume
(fL) | Buffered | | PP-IP5-K | Osc_Ca_
IP3metabolism
Accession No. : 24 | IHP-system
Pathway No. : 130 | 0.057 | 1000 | No | | from Huang et al, Biochem 37; 1998: 14998-15004 |
PP-IP5-K acting as a Substrate in a reaction in Osc_Ca_IP3metabolism Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | | PP-IP5cmplx-on | Osc_Ca_
IP3metabolism
Accession No. : 24 | IHP-system
Pathway No. : 130 | 0.0027
(uM^-2 s^-1) | 2.5
(s^-1) | - | - | Substrate
ATP
PP-IP5
PP-IP5-K
Product
PP-IP5-K-complex
| | from Huang et al, Biochem 37; 1998 Kf calculated using Km for PP-InsP5 and ATP, and Vmax of forward and backward reactions. Kb = Vmax of backward reaction |
PP-IP5-K acting as a Product in a reaction in Osc_Ca_IP3metabolism Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | | PP-IP5cmplx-off | Osc_Ca_
IP3metabolism
Accession No. : 24 | IHP-system
Pathway No. : 130 | 1
(s^-1) | 0.0013
(uM^-2 s^-1) | - | - | Substrate
PP-IP5-K-complex
Product
ADP
PP-IP5-K
bisPP-IP4
| | from Huang et al, Biochem 37; 1998 Kf = Vmax of forward reaction Kb calculated using Km for PP-InsP5 and ATP, and Vmax of forward and backward reactions |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
|
