Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.

Search in:

ALL Accession Pathway Molecule Enzyme Reaction Connected to

Search for

Match

Anything Exact Word Starting With

By

Name Notes Model

Molecule Parameter List for CaMKII***

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

CaMKII*** participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	1	0	2	2	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
fig4_synapse	3	Network	Shared_Object_fig4_synapse,  PKC,  PLA2,   PLCbeta,  Gq,  MAPK,   Ras,  CaMKII,  CaM,   PP1,  PP2B,  PKA,   AC
This is the composite model of 4 kinases: PKC, MAPK, PKA and CaMKII and numerous regulatory pathways involved in synaptic signaling. From Bhalla US and Iyengar R. Science (1999) 283(5400):381-7.This model comes from figure 4 of that paper. Demonstration script files for generating the figures in the paper, including figure 4, are available here.

CaMKII*** acting as a Molecule in  fig4_synapse Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
CaMKII***	fig4_synapse Accession No. : 3	CaMKII Pathway No. : 26	0	1000	No

CaMKII*** acting as a Summed Molecule in  fig4_synapse Network

Accession Name	Pathway Name	Target	Input
fig4_synapse Accession No. : 3	CaMKII Pathway No. : 26	tot_autonomous_CaMKII	CaMKII-thr286 CaMKII***

CaMKII*** acting as a Substrate for an Enzyme in  fig4_synapse Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PP1-active  / Deph-thr305	fig4_synapse Accession No. : 3	Shared_Object_ fig4_synapse Pathway No. : 19	5.09907	0.35	4	explicit E-S complex	Substrate CaMKII*** Product CaMKII-thr286
2	PP1-active  / Deph-thr286c	fig4_synapse Accession No. : 3	Shared_Object_ fig4_synapse Pathway No. : 19	5.09907	0.35	4	explicit E-S complex	Substrate CaMKII*** Product CaMK-thr306

CaMKII*** acting as a Product of an Enzyme in  fig4_synapse Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	tot_CaM_CaMKII  / CaM_act_305	fig4_synapse Accession No. : 3	CaMKII Pathway No. : 26	0.00000270563	6	4	explicit E-S complex	Substrate CaMKII-thr286 Product CaMKII***
2	tot_autonomous_ CaMKII  / auton_305	fig4_synapse Accession No. : 3	CaMKII Pathway No. : 26	0.00000416667	6	4	explicit E-S complex	Substrate CaMKII-thr286 Product CaMKII***