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Molecule Parameter List for basal_CaMKII_PSD

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
basal_CaMKII_PSD participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1100001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
CaMKII_model363Network
Shared_Object_CaMKII_model3,  CaMKII,  CaM,  
PP1,  PP2B,  PP1_PSD,  
AC,  PKA 
This is the complete model of CaMKII bistability, model 3. It exhibits bistability in CaMKII activation due to autophosphorylation at the PSD and local saturation of PP1. This version of model 3 includes PKA regulatory input. This has little effect on the deterministic calculations, but the PKA pathway introduces a lot of noise which causes a difference in stochastic runs.

basal_CaMKII_PSD acting as a Molecule in  CaMKII_model3 Network
NameAccession NamePathway NameInitial Conc.
(uM)		Volume
(fL)		Buffered
basal_CaMKII_PSDCaMKII_model3
Accession No. : 63
  • Shared_Object_
    CaMKII_model3
    Pathway No. : 263
    		• 20.01No

    basal_CaMKII_PSD acting as a Summed Molecule in      CaMKII_model3 Network
    Accession NamePathway NameTargetInput
    CaMKII_model3
    Accession No. : 63
  • Shared_Object_
    CaMKII_model3
    Pathway No. : 263
    		• tot-auto-PSD
  • CaMKII-thr286-PS
    D
    CaMKII***-PSD
  • basal_CaMKII_
    PSD

    • basal_CaMKII_PSD acting as a Product in a reaction in      CaMKII_model3 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
  • Stoch_Basal_
    CaMKII_PSD
    		• CaMKII_model3
    Accession No. : 63
  • Shared_Object_
    CaMKII_model3
    Pathway No. : 263
    		• 1
    (s^-1)    		1
    (s^-1)    		Keq = 1(uM)0.5secSubstrate
  • basal_CaMKII_
    PSD_control

    Product
  • basal_CaMKII_
    PSD


    • Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.