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Molecule Parameter List for act_CaMKII_cyt

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
act_CaMKII_cyt participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1300000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
CaMKII_model363Network
Shared_Object_CaMKII_model3,  CaMKII,  CaM,  
PP1,  PP2B,  PP1_PSD,  
AC,  PKA 
This is the complete model of CaMKII bistability, model 3. It exhibits bistability in CaMKII activation due to autophosphorylation at the PSD and local saturation of PP1. This version of model 3 includes PKA regulatory input. This has little effect on the deterministic calculations, but the PKA pathway introduces a lot of noise which causes a difference in stochastic runs.

act_CaMKII_cyt acting as a Molecule in  CaMKII_model3 Network
NameAccession NamePathway NameInitial Conc.
(uM)		Volume
(fL)		Buffered
act_CaMKII_cytCaMKII_model3
Accession No. : 63
  • Shared_Object_
    CaMKII_model3
    Pathway No. : 263
    		• 20.09No

    act_CaMKII_cyt acting as a Summed Molecule in      CaMKII_model3 Network
     Accession NanePathway NameTargetInput
    1CaMKII_model3
    Accession No. : 63    		CaMKII
    Pathway No. : 264    		tot_CaM_CaMKIICaMKII-CaM
  • CaMKII-thr286*-C
    aM
    • 2CaMKII_model3
    Accession No. : 63
  • Shared_Object_
    CaMKII_model3
    Pathway No. : 263
    		• act_CaMKII_cyttot_CaM_CaMKII
  • tot_autonomous_
    CaMKII
    • 3CaMKII_model3
    Accession No. : 63    		CaMKII
    Pathway No. : 264    		tot_autonomous_CaMKIICaMKII-thr286
    CaMKII***
  • basal_CaMKII_
    cyt


    • Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.