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Molecule Parameter List for MAPK* | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | Statistics | Accession and Pathway Details | |
Accession Name | Accession No. | Accession Type | Pathway Link | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 | 82 | Network | Shared_Object_Ajay_Bhalla_2007_ReacDiff1_1e-13, PKC, MAPK, Ras, CaM, PKM, chain, kinetics, PKC, MAPK, Ras, CaM, PKM, kinetics[1], PKC, MAPK, Ras, CaM, PKM, kinetics[2], PKC, MAPK, Ras, CaM, PKM, kinetics[3], PKC, MAPK, Ras, CaM, PKM, kinetics[4], PKC, MAPK, Ras, CaM, PKM, kinetics[5], PKC, MAPK, Ras, kinetics[6], CaM, PKM, PKC, MAPK, Ras, CaM, PKM, kinetics[7], PKC, MAPK, Ras, CaM, PKM, kinetics[8], PKC, MAPK, Ras, CaM, PKM, kinetics[9], PKC, MAPK, Ras, CaM, PKM, kinetics[10], PKC, MAPK, Ras, CaM, PKM, kinetics[11], PKC, MAPK, Ras, CaM, PKM, kinetics[12], PKC, MAPK, Ras, CaM, PKM, kinetics[13], PKC, MAPK, Ras, CaM, PKM, kinetics[14], PKC, MAPK, Ras, CaM, PKM, kinetics[15], PKC, MAPK, Ras, CaM, PKM, kinetics[16], PKC, MAPK, Ras, CaM, PKM, kinetics[17], PKC, MAPK, Ras, CaM, PKM, kinetics[18], PKC, MAPK, Ras, CaM, PKM, kinetics[19], PKC, MAPK, Ras, CaM, PKM, kinetics[20], PKC, MAPK, Ras, CaM, PKM, kinetics[21], PKC, MAPK, Ras, CaM, PKM, kinetics[22], PKC, MAPK, Ras, CaM, PKM, kinetics[23], PKC, MAPK, Ras, CaM, PKM | This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.
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MAPK* acting as a Molecule in Ajay_Bhalla_2007_ReacDiff1_1e-13 Network
MAPK* acting as an Enzyme in Ajay_Bhalla_2007_ReacDiff1_1e-13 Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | 1 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 2 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics Pathway No. : 533 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 3 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[1] Pathway No. : 539 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 4 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[2] Pathway No. : 545 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 5 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[3] Pathway No. : 551 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 6 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[4] Pathway No. : 557 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 7 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[5] Pathway No. : 563 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 8 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[6] Pathway No. : 567 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 9 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[7] Pathway No. : 575 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 10 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[8] Pathway No. : 581 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 11 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[9] Pathway No. : 587 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 12 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[10] Pathway No. : 593 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 13 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[11] Pathway No. : 599 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 14 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[12] Pathway No. : 605 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 15 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[13] Pathway No. : 611 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 16 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[14] Pathway No. : 617 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 17 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[15] Pathway No. : 623 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 18 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[16] Pathway No. : 629 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 19 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[17] Pathway No. : 635 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 20 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[18] Pathway No. : 641 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 21 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[19] Pathway No. : 647 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 22 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[20] Pathway No. : 653 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 23 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[21] Pathway No. : 659 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 24 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[22] Pathway No. : 665 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 25 | MAPK* / MAPK*-feedback
| Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | kinetics[23] Pathway No. : 671 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. |
MAPK* acting as a Substrate for an Enzyme in Ajay_Bhalla_2007_ReacDiff1_1e-13 Network
MAPK* acting as a Product of an Enzyme in Ajay_Bhalla_2007_ReacDiff1_1e-13 Network
MAPK* acting as a Substrate in a reaction in Ajay_Bhalla_2007_ReacDiff1_1e-13 Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
MAPK* acting as a Product in a reaction in Ajay_Bhalla_2007_ReacDiff1_1e-13 Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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