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Molecule Parameter List for inact-GEF

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

*inact-GEF* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	40	0	40	40	0	79	79

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Ajay_Bhalla_ 2007_ReacDiff2	83	Network	Shared_Object_Ajay_Bhalla_2007_ReacDiff, PKC, MAPK, Ras, CaM, PKM, chain, kinetics, PKC, MAPK, Ras, CaM, PKM, kinetics[1], PKC, MAPK, Ras, kinetics[3], CaM, PKM, kinetics[2], PKC, MAPK, Ras, CaM, PKM, PKC, MAPK, Ras, CaM, PKM, kinetics[4], PKC, MAPK, Ras, CaM, PKM, kinetics[5], PKC, MAPK, Ras, CaM, PKM, kinetics[6], PKC, MAPK, Ras, CaM, PKM, kinetics[7], PKC, MAPK, Ras, CaM, PKM, kinetics[8], PKC, MAPK, Ras, CaM, PKM, kinetics[9], PKC, MAPK, Ras, CaM, PKM, kinetics[10], PKC, MAPK, Ras, CaM, PKM, kinetics[11], PKC, MAPK, Ras, CaM, PKM, kinetics[12], PKC, MAPK, Ras, CaM, PKM, kinetics[13], PKC, MAPK, Ras, CaM, PKM, kinetics[14], PKC, MAPK, Ras, CaM, PKM, kinetics[15], PKC, MAPK, Ras, CaM, PKM, kinetics[16], PKC, MAPK, Ras, CaM, PKM, kinetics[17], PKC, MAPK, Ras, CaM, PKM, kinetics[18], PKC, MAPK, Ras, CaM, PKM, kinetics[19], PKC, MAPK, Ras, CaM, PKM, kinetics[20], PKC, MAPK, Ras, CaM, PKM, kinetics[21], PKC, MAPK, Ras, CaM, PKM, kinetics[22], PKC, MAPK, Ras, CaM, PKM, kinetics[23], PKC, MAPK, Ras, CaM, PKM, kinetics[24], PKC, MAPK, Ras, CaM, PKM, kinetics[25], PKC, MAPK, Ras, CaM, PKM, kinetics[26], PKC, MAPK, Ras, CaM, PKM, kinetics[27], PKC, MAPK, Ras, CaM, PKM, kinetics[28], PKC, MAPK, Ras, CaM, PKM, kinetics[29], PKC, MAPK, Ras, CaM, PKM, kinetics[30], PKC, MAPK, Ras, CaM, PKM, kinetics[31], PKC, MAPK, Ras, CaM, PKM, kinetics[32], PKC, MAPK, Ras, CaM, PKM, kinetics[33], PKC, MAPK, Ras, CaM, PKM, kinetics[34], PKC, MAPK, Ras, CaM, PKM, kinetics[35], PKC, MAPK, Ras, CaM, PKM, kinetics[36], PKC, MAPK, Ras, CaM, PKM, kinetics[37], PKC, MAPK, Ras, CaM, PKM, kinetics[38], PKC, MAPK, Ras, CaM, PKM
This is a 40-compartment reaction-diffusion-transport version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 40 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec In addition, we have a forward (dendrite to soma) transport term of 1 microns/sec. This converts to a rate of 0.1/sec, but applies only to the kf. So the total kf of the diffusion 'reaction' is 0.11 for D = 1 micron^2/sec, and kb is 0.01. If D=0.1 micron^2/sec then kf = 0.101 and kb = 0.001. In addition this model has all molecules buffered in the first and last compartments. This boundary conditions says that the molecules are not drained out of the first compartment, nor do they all pile up in the last one. The stimulus file pkm_mapk22_transp_endbuf_D1e-13_Fig4CD which was used for the model to replicate Figure 4C and 4D from the paper.

inact-GEF acting as a Molecule in Ajay_Bhalla_2007_ReacDiff2 Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 687	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 693	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 700	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 705	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 711	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 717	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 723	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 729	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 735	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 741	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 747	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 753	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 759	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 765	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 771	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 777	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 783	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 789	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 795	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 801	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 807	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 813	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 819	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 825	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 831	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 837	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 843	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 849	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 855	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 861	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 867	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 873	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 879	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 885	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 891	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 897	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 903	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 909	0.0848	1.5	No
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 680	0.0848	1.5	Yes
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.
inact-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 915	0.0848	1.5	Yes
Assume that SoS is present only at 50 nM. Revised to 100 nM to get equil to experimentally known levels.

inact-GEF acting as an Enzyme in Ajay_Bhalla_2007_ReacDiff2 Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 680	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

2	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 687	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

3	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 693	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

4	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 700	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

5	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 705	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

6	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 711	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

7	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 717	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

8	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 723	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

9	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 729	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

10	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 735	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

11	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 741	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

12	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 747	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

13	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 753	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

14	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 759	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

15	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 765	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

16	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 771	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

17	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 777	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

18	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 783	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

19	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 789	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

20	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 795	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

21	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 801	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

22	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 807	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

23	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 813	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

24	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 819	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

25	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 825	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

26	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 831	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

27	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 837	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

28	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 843	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

29	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 849	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

30	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 855	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

31	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 861	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

32	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 867	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

33	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 873	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

34	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 879	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

35	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 885	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

36	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 891	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

37	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 897	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

38	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 903	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

39	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 909	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

40	inact-GEF / basal_GEF_ activity	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 915	10.1015	0.02	4	explicit E-S complex	Substrate GDP-Ras Product GTP-Ras

inact-GEF acting as a Substrate for an Enzyme in Ajay_Bhalla_2007_ReacDiff2 Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
2	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics Pathway No. : 684	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
3	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[1] Pathway No. : 690	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
4	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[2] Pathway No. : 697	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
5	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[3] Pathway No. : 694	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
6	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[4] Pathway No. : 708	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
7	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[5] Pathway No. : 714	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
8	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[6] Pathway No. : 720	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
9	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[7] Pathway No. : 726	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
10	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[8] Pathway No. : 732	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
11	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[9] Pathway No. : 738	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
12	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[10] Pathway No. : 744	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
13	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[11] Pathway No. : 750	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
14	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[12] Pathway No. : 756	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
15	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[13] Pathway No. : 762	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
16	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[14] Pathway No. : 768	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
17	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[15] Pathway No. : 774	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
18	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[16] Pathway No. : 780	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
19	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[17] Pathway No. : 786	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
20	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[18] Pathway No. : 792	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
21	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[19] Pathway No. : 798	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
22	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[20] Pathway No. : 804	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
23	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[21] Pathway No. : 810	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
24	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[22] Pathway No. : 816	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
25	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[23] Pathway No. : 822	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
26	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[24] Pathway No. : 828	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
27	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[25] Pathway No. : 834	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
28	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[26] Pathway No. : 840	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
29	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[27] Pathway No. : 846	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
30	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[28] Pathway No. : 852	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
31	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[29] Pathway No. : 858	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
32	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[30] Pathway No. : 864	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
33	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[31] Pathway No. : 870	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
34	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[32] Pathway No. : 876	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
35	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[33] Pathway No. : 882	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
36	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[34] Pathway No. : 888	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
37	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[35] Pathway No. : 894	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
38	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[36] Pathway No. : 900	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
39	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[37] Pathway No. : 906	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X
40	PKC-active / PKC-act-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	kinetics[38] Pathway No. : 912	3.33333	4	4	explicit E-S complex	Substrate inact-GEF Product GEF*
	Rate consts from PKC-act-raf. This reaction activates GEF. It can lead to at least 2X stim of ras, and a 2X stim of MAPK over and above that obtained via direct phosph of c-raf. Note that it is a push-pull reaction, and there is also a contribution through the phosphorylation and inactivation of GAPs. The original PKC-act-raf rate consts are too fast. We lower K1 by 10 X

inact-GEF acting as a Substrate in a reaction in Ajay_Bhalla_2007_ReacDiff2 Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
2	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 680	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
3	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
4	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 687	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
5	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
6	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 693	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
7	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
8	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 700	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
9	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
10	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 705	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
11	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
12	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 711	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
13	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
14	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 717	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
15	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
16	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 723	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
17	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
18	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 729	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
19	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
20	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 735	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
21	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
22	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 741	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
23	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
24	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 747	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
25	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
26	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 753	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
27	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
28	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 759	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
29	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
30	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 765	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
31	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
32	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 771	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
33	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
34	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 777	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
35	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
36	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 783	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
37	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
38	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 789	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
39	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
40	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 795	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
41	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
42	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 801	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
43	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
44	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 807	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
45	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
46	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 813	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
47	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
48	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 819	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
49	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
50	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 825	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
51	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
52	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 831	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
53	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
54	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 837	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
55	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
56	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 843	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
57	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
58	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 849	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
59	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
60	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 855	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
61	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
62	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 861	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
63	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
64	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 867	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
65	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
66	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 873	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
67	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
68	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 879	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
69	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
70	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 885	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
71	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
72	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 891	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
73	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
74	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 897	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
75	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
76	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 903	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
77	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
78	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 909	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
79	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 915	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995

inact-GEF acting as a Product in a reaction in Ajay_Bhalla_2007_ReacDiff2 Network

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 680	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
2	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
3	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 687	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
4	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
5	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 693	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
6	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
7	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 700	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
8	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
9	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 705	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
10	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
11	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 711	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
12	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
13	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 717	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
14	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
15	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 723	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
16	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
17	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 729	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
18	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
19	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 735	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
20	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
21	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 741	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
22	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
23	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 747	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
24	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
25	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 753	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
26	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
27	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 759	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
28	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
29	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 765	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
30	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
31	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 771	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
32	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
33	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 777	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
34	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
35	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 783	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
36	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
37	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 789	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
38	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
39	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 795	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
40	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
41	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 801	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
42	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
43	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 807	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
44	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
45	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 813	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
46	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
47	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 819	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
48	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
49	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 825	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
50	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
51	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 831	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
52	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
53	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 837	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
54	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
55	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 843	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
56	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
57	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 849	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
58	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
59	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 855	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
60	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
61	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 861	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
62	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
63	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 867	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
64	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
65	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 873	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
66	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
67	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 879	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
68	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
69	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 885	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
70	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
71	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 891	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
72	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
73	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 897	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
74	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
75	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 903	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
76	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
77	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 909	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF
78	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate inact-GEF Product inact-GEF
79	dephosph-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 915	1 (s^-1)	0 (s^-1)	-	-	Substrate GEF* Product inact-GEF

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