| | Molecule Name/
Site Name | Km (uM) | kcat (1/s) | Ratio
(k2/k3) | Enzyme Type | Substrate | Product |
| 1 |
Enzyme Activity:
dipp_ip7
Enzyme Molecule:
DIPP1 | 0.340006 | 5.1 | 4 | explicit E-S complex | PP-IP5
| IP6
|
| | from Safrany et al, EMBO J 17(22); 1998 Vmax represents activity of recombinant human protein which is 20-50 fold greater than activity of the purified rat enzyme |
| 2 |
Enzyme Activity:
dipp_ip8
Enzyme Molecule:
DIPP1 | 0.0340035 | 0.6165 | 4 | explicit E-S complex | bisPP-IP4
| PP-IP5
|
| | from Safrany et al, EMBO J 17(22); 1998 Vmax represents activity of human recombinant protein, which is 20-50 fold greater than activity of the purified rat enzyme |
| 3 |
Enzyme Activity:
ip5_k1
Enzyme Molecule:
IP6-K | 6.69999 | 0.234 | 4 | explicit E-S complex | IP5(13456)
| PP-IP4
|
| | from Saiardi et al, JBC 275(32); 2000: 24686-92 |
| 4 |
Enzyme Activity:
ip5_k2
Enzyme Molecule:
IP6_K2 | 8.4 | 0.0572 | 4 | explicit E-S complex | IP5(13456)
| PP-IP4
|
| | from Saiardi et al, JBC 275(32); 2000: 24686-92 |
| 5 |
Enzyme Activity:
ip6_k2
Enzyme Molecule:
IP6_K2 | 2.99999 | 1.633 | 4 | explicit E-S complex | IP6
| PP-IP5
|
| | from Saiardi et al, Curr Biol 9; 1999 |
| 6 |
Enzyme Activity:
pp-ip4-k1
Enzyme Molecule:
IP6-K | 23.0003 | 0.05 | 4 | explicit E-S complex | PP-IP4
| bisPP-IP3
|
| | from Saiardi et al, JBC 275; 2000 approx Km and Vmax calculated from first order rate constants |
| 7 |
Enzyme Activity:
pp-ip4-k2
Enzyme Molecule:
IP6_K2 | 30.0003 | 0.01 | 4 | explicit E-S complex | PP-IP4
| bisPP-IP3
|
| | from Saiardi et al, JBC 275; 2000 approx Km and Vmax calculated from first order rate constants |
