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Enzyme List for pathway Othmer-Tang-model (Pathway Number 171)

 Molecule Name/
Site Name
Km (uM) kcat (1/s)Ratio
(k2/k3)
Enzyme TypeSubstrate Product
1 Enzyme Activity:
ER_pump

Enzyme Molecule:
ER_pump
0.15104explicit E-S complexCa
Ca-sequester
  Othmer and Tang use a Km of 0.5 uM, but this does not generate proper Ca oscillations in our model. So we have decreased Km to 0.15 uM. This is closer to the 0.1 uM value used by Keizer and De Young in Tang et al, Biophys J 70, 1996

Pathway DetailMolecule ListEnzyme ListReaction List