| Name | Initial Conc. (uM) td> | Volume (fL) | Buffered |
1 | activeIP3R | 0 | 1000 | No |
| This represents the active IP3 Receptor channel that conducts Ca across the ER membrane in the Othmer-Tang model. Its 0 uM initial concentration represents no active channels present under basal conditions. Its levels build up upon stimulation. |
2 | Ca.IP3.IP3R | 0 | 1000 | No |
| IP3-IP3Receptor complex with Ca bound at the activating site. |
3 | Ca2.IP3.IP3R | 0 | 1000 | No |
| THe Ca-IP3-IP3Receptor complex with additional Ca bound to the inhibitory sites. This is the inactive state of the channel. |
4 | ER_leak | 2 | 1000 | No |
| The channel that leaks Ca from the stores to the cytoplasm This channel is not sensitive to any potential differences. Channel permeability is 0.1, as used in the O-T model (Tang et al, Biophys J 70, 1996) |
5 | ER_pump | 2 | 1000 | No |
| This pump represents the ATP-dependent pump that moves cytosolic Ca into the ER in the Othmer-Tang model. |
6 | IP3 | 0.2 | 1000 | No |
| Inositol(145)trisphosphate in the cytoplasm. Levels are determined by the IP3-metabolism network |
7 | IP3.IP3R | 0 | 1000 | No |
| IP3 Receptor with IP3 bound. This state does not conduct Ca as per Tang et al, Biophys J 70; 1996 |
8 | IP3R | 0.1 | 1000 | No |
| IP3 Receptor with no ligand bound |
9 | mirror_Ca.IP3.IP3R | 0 | 1000 | No |
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