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Parameters for Othmer-Tang-model (Pathway Number 133)

Pathway Layout

Pathway Basic Parameters

Pathway NameOthmer-Tang-model
Pathway Entry Number 133
Accession Number 24
Accession Name Osc_Ca_IP3metabolism
Species Generic mammalian
Tissue Brain - Neuronal
CellCompartmentCytosol
Related Pathways 171
Notes The Othmer-Tang kinetic model for the InsP3 receptor with oscillatory Ca dynamics. This model incorporates both positive and negative feedback from calcium. The active IP3 receptor channel has one Ca and one IP3 bound. The inactive state of the channel (post-activation) is represented by 2 Ca and one IP3 bound to the IP3 receptor. Parameters in this model are as far as possible identical to those used by Othmer and Tang (Tang et al, Biophys J 70; 1996: 246-63).

Statistics

9
1
4

Conversion format

This pathway is part of accession 24 and is completely specified in the file acc24.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc24.g   
GENESIS Format (Annotated version)    Anno_acc24.g   
Pathway DetailMolecule ListEnzyme ListReaction List