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Molecule Parameter List for Anchor

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
Anchor participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000044

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • AMPAR_traff_
    model1
  • 60Network
    Shared_Object_AMPAR_traff_model1 CaMKII CaM 
    PP1 PP2B PP1_PSD 
    PKA AC AMPAR 
    AMPAR_memb 
    This is the basic model of AMPAR trafficking bistability. It is based on Hayer and Bhalla, PLoS Comput. Biol. 2005. It includes the degradation and turnover of AMPARs. The CaMKII portion of the model is not bistable.

    Anchor acting as a Molecule in  
    AMPAR_traff_model1 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    Anchor
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR_memb
    Pathway No. : 253
    27.33330.01No

    Anchor acting as a Substrate in a reaction in  
    AMPAR_traff_model1 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1exo_reg**
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    0.0002
    (#^-1 s^-1)
    0.008
    (s^-1)
    Not applicable**-Substrate
  • A835*845*_
    B835*845*

    Anchor

    Product
  • A835*845*_
    B835*845*

  • 2exo_reg_*
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    0.0002
    (#^-1 s^-1)
    0.008
    (s^-1)
    Not applicable**-Substrate
    A845*_B831*845*
    Anchor

    Product
    A845*_B831*845*
    3exo_reg*_
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    0.0002
    (#^-1 s^-1)
    0.008
    (s^-1)
    Not applicable**-Substrate
    A831*845*_B845*
    Anchor

    Product
    A831*845*_B845*
    4exo_reg__
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    0.0002
    (#^-1 s^-1)
    0.008
    (s^-1)
    Not applicable**-Substrate
    A845*_B845*
    Anchor

    Product
    A845*_B845*
      Exo rates are scaled from earlier model versions to account for binding of anchor. We have about 200 molecules of anchor in the whole model. Here we select rates to give us a max of about 150 molecules of GluR at the synapse.
    ** This is a trasport reation between compartments of different volumes. Therefore Kd is not applicable. Please Note Kf, Kb units are in number of molecules instead of concentration

    Anchor acting as a Product in a reaction in  
    AMPAR_traff_model1 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1recycle**
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    0.0008
    (s^-1)
    0
    (#^-1 s^-1)
    Not applicable**-Substrate
    A831*_B831*

    Product
    A831*_B831*
    Anchor
    2recycle_*
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    0.0008
    (s^-1)
    0
    (#^-1 s^-1)
    Not applicable**-Substrate
    A_B831*

    Product
    A_B831*
    Anchor
    3recycle*_
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    0.0008
    (s^-1)
    0
    (#^-1 s^-1)
    Not applicable**-Substrate
    A831*_B

    Product
    A831*_B
    Anchor
    4recycle__
  • AMPAR_traff_
    model1

    Accession No. : 60
  • AMPAR
    Pathway No. : 252
    0.0008
    (s^-1)
    0
    (#^-1 s^-1)
    Not applicable**-Substrate
    A_B

    Product
    A_B
    Anchor
    ** This is a trasport reation between compartments of different volumes. Therefore Kd is not applicable. Please Note Kf, Kb units are in number of molecules instead of concentration



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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