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Molecule Parameter List for PKC-Ca

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
PKC-Ca participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences2500007449

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13
  • 82NetworkShared_Object_Ajay_Bhalla_2007_ReacDiff1_1e-13 
    PKC MAPK Ras CaM PKM chain kinetics PKC MAPK Ras CaM PKM kinetics[1] 
    PKC MAPK Ras CaM PKM kinetics[2] PKC MAPK Ras CaM PKM kinetics[3] 
    PKC MAPK Ras CaM PKM kinetics[4] PKC MAPK Ras CaM PKM kinetics[5] 
    PKC MAPK Ras kinetics[6] CaM PKM PKC MAPK Ras CaM PKM kinetics[7] 
    PKC MAPK Ras CaM PKM kinetics[8] PKC MAPK Ras CaM PKM kinetics[9] 
    PKC MAPK Ras CaM PKM kinetics[10] PKC MAPK Ras CaM PKM kinetics[11] 
    PKC MAPK Ras CaM PKM kinetics[12] PKC MAPK Ras CaM PKM kinetics[13] 
    PKC MAPK Ras CaM PKM kinetics[14] PKC MAPK Ras CaM PKM kinetics[15] 
    PKC MAPK Ras CaM PKM kinetics[16] PKC MAPK Ras CaM PKM kinetics[17] 
    PKC MAPK Ras CaM PKM kinetics[18] PKC MAPK Ras CaM PKM kinetics[19] 
    PKC MAPK Ras CaM PKM kinetics[20] PKC MAPK Ras CaM PKM kinetics[21] 
    PKC MAPK Ras CaM PKM kinetics[22] PKC MAPK Ras CaM PKM kinetics[23] 
    PKC MAPK Ras CaM PKM 
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
    The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
    pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
    pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.

    PKC-Ca acting as a Molecule in  
    Ajay_Bhalla_2007_ReacDiff1_1e-13 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 527
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 534
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 540
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 546
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 552
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 558
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 564
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 570
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 576
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 582
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 588
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 594
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 600
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 606
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 612
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 618
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 624
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 630
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 636
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 642
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 648
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 654
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 660
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 666
    01.5No
    PKC-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 672
    01.5No

    PKC-Ca acting as a Substrate in a reaction in  
    Ajay_Bhalla_2007_ReacDiff1_1e-13 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    2PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 527
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    3PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 527
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    4diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    5diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    6PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 534
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    7PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 534
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    8diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    9PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 552
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    10PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 552
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    11PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 540
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    12PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 540
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    13diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    14PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 546
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    15PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 546
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    16diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    17PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 576
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    18PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 576
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    19diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    20PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 558
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    21PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 558
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    22diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    23PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 564
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    24PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 564
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    25diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    26PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 570
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    27PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 570
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    28diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    29PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 624
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    30PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 624
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    31diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    32PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 582
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    33PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 582
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    34diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    35PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 588
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    36PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 588
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    37diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    38PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 594
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    39PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 594
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    40diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    41PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 600
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    42PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 600
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    43diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    44PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 606
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    45PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 606
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    46diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    47PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 612
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    48PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 612
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    49diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    50PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 618
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    51PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 618
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    52diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    53PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 630
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    54PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 630
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    55diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    56PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 636
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    57PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 636
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    58diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    59PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 642
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    60PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 642
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    61diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    62PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 648
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    63PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 648
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    64diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    65PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 654
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    66PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 654
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    67diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    68PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 660
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    69PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 660
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    70diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    71PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 666
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    72PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 666
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*
    73PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 672
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    74PKC-Ca-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 672
    1.2705
    (s^-1)
    3.5026
    (s^-1)
    Keq = 2.7569(uM)0.21secSubstrate
    PKC-Ca

    Product
    PKC-Ca-memb*

    PKC-Ca acting as a Product in a reaction in  
    Ajay_Bhalla_2007_ReacDiff1_1e-13 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    2PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 527
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    3diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    4diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    5PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 534
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    6diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    7PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 552
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    8PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 540
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    9diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    10PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 546
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    11diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    12PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 576
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    13diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    14PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 558
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    15diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    16PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 564
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    17diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    18PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 570
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    19diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    20PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 624
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    21diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    22PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 582
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    23diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    24PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 588
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    25diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    26PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 594
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    27diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    28PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 600
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    29diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    30PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 606
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    31diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    32PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 612
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    33diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    34PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 618
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    35diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    36PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 630
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    37diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    38PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 636
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    39diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    40PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 642
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    41diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    42PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 648
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    43diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    44PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 654
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    45diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    46PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 660
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    47diff
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Pathway No. : 526
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PKC-Ca

    Product
    PKC-Ca
    48PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 666
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
    49PKC-act-by-Ca
  • Ajay_Bhalla_
    2007_ReacDiff1_
    1e-13

    Accession No. : 82
  • PKC
    Pathway No. : 672
    0.6
    (uM^-1 s^-1)
    0.5
    (s^-1)
    Kd(bf) = 0.8333(uM)-Substrate
    Ca
    PKC-cytosolic

    Product
    PKC-Ca
      Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5



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