| |
Name | Accession Name /
Accession No. | Pathway Name /
Pathway No. | Accession
Type | Initial
Conc.
(uM) | Volume
(fL) | Buffered | Sum Total Of |
| 41 | CaMKII | NonOsc_Ca_
IP3metabolism
Accession No. 31 | CaMKII
Pathway No. 145 | Network | 70 | 1000 | No | - |
| | Huge concentration of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. This comes to about 70 uM. Seen the review: Hanson and Schulman 1992 Ann. Rev. Biuochem 60:559-601 |
| 42 | CaMKII | Osc_Ca_
IP3metabolism
Accession No. 32 | CaMKII
Pathway No. 159 | Network | 70 | 1000 | No | - |
| | Huge concentration of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. This comes to about 70 uM. Seen the review: Hanson and Schulman 1992 Ann. Rev. Biuochem 60:559-601 |
| 43 | CaMKII | CaMKII
Accession No. 33 | CaMKII
Pathway No. 174 | Network | 12.7325 | 0.1309 | No | - |
| | Init level is 100 holoenzymes of 10 subunits each. |
| 44 | CaMKII | CaMKII_2003
Accession No. 49 | CaMKII
Pathway No. 202 | Network | 70 | 1000 | No | - |
| | Huge conc of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. This comes to about 70 uM. |
| 45 | CaMKII | MAPK_network_
2003
Accession No. 50 | CaMKII
Pathway No. 216 | Network | 70 | 1000 | No | - |
| | Huge conc of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. This comes to about 70 uM. |
| 46 | CaMKII | AMPAR_traff_
model0
Accession No. 59 | CaMKII
Pathway No. 235 | Network | 20 | 0.09 | No | - |
| | Huge conc of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. This comes to about 70 uM. |
| 47 | CaMKII | AMPAR_traff_
model1
Accession No. 60 | CaMKII
Pathway No. 245 | Network | 20 | 0.09 | No | - |
| | Huge conc of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. This comes to about 70 uM. |
| 48 | CaMKII | CaMKII_noPKA_
model3
Accession No. 62 | CaMKII
Pathway No. 258 | Network | 20 | 0.09 | No | - |
| | Huge conc of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. |
| 49 | CaMKII | CaMKII_model3
Accession No. 63 | CaMKII
Pathway No. 264 | Network | 20 | 0.09 | No | - |
| | Huge conc of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. |
| 50 | CaMKII | AMPAR_CaMKII_
strong_coupling
Accession No. 64 | CaMKII
Pathway No. 272 | Network | 20 | 0.09 | No | - |
| | Huge conc of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. This comes to about 70 uM. |
| 51 | CaMKII | AMPAR_CaMKII_
weak_coupling
Accession No. 65 | CaMKII
Pathway No. 282 | Network | 20 | 0.09 | No | - |
| | Huge conc of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. This comes to about 70 uM. |
| 52 | CaMKII | Ajay_Bhalla_
2004_PKM_Tuning
Accession No. 76 | CaMKII
Pathway No. 322 | Network | 70 | 1.5 | No | - |
| | Huge conc of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. This comes to about 70 uM. |
| 53 | CaMKII | Ajay_Bhalla_
2004_PKM_MKP3_
Tuning
Accession No. 77 | CaMKII
Pathway No. 339 | Network | 70 | 1.5 | No | - |
| | Huge conc of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. This comes to about 70 uM. |
| 54 | CaMKII | Ajay_Bhalla_
2004_Feedback_
Tuning
Accession No. 78 | CaMKII
Pathway No. 357 | Network | 70 | 1.5 | No | - |
| | Huge conc of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. This comes to about 70 uM. |
| 55 | CaMKII | BCM
Accession No. 96 | bcm
Pathway No. 1118 | Pathway | 10 | 1.66667 | No | - |
| 56 | CaMKII | bcm
Accession No. 107 | CaMKII_g
Pathway No. 1138 | Pathway | 1.9642 | 0 | No | - |
| 57 | CaMKII | bcm_bistable
Accession No. 108 | CaMKII_g
Pathway No. 1142 | Pathway | 5 | 0 | No | - |
| 58 | CaMKII*** | fig3_CaMKII
Accession No. 2 | CaMKII
Pathway No. 13 | Network | 0 | 1000 | No | - |
| 59 | CaMKII*** | fig4_synapse
Accession No. 3 | CaMKII
Pathway No. 26 | Network | 0 | 1000 | No | - |
| 60 | CaMKII*** | Synaptic_
Network
Accession No. 16 | CaMKII
Pathway No. 80 | Network | 0 | 1000 | No | - |
| | From Hanson and Schulman, the CaMKII does a lot of autophosphorylation just after the CaM is released. This prevents further CaM binding and renders the enzyme quite independent of Ca. |
arrow indicates that ordering is done according to ascending or descending order.
and 
color.