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Molecule Parameter List for Ca | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Ca participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| PLCbeta1 | 13 | Pathway | PLCbeta |
| This is a model of PLCbeta1 in the bovine brain membranes as stimulated by Ca, Gq and PA. The primary data sources are Irene Litosch Biochemistry (2000) 39(26):7736-43, Sternweis PC et al. Philos Trans R Soc Lond B Biol Sci. (1992) 336(1276):35-41 and Smrcka AV et al. Science (1991) 251(4995):804-7. | |||
Ca acting as a Molecule in PLCbeta1 Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| Ca | PLCbeta1 Accession No. : 13 | PLCbeta Pathway No. : 67 | 0.09 | 0.0016667 | Yes | |
| 21 Jul 2001 Concn varies betwn 0.001 to 10 uM. The Concentration of Ca is obtained from I. Litosch, Biochem., 2000, 39,7736-7743. The concentration of Ca is buffered to different levels and rate of binding of enzyme is noted.But here it is set to 0.09uM which is the basal level of Calcium. | ||||||
Ca acting as a Substrate in a reaction in PLCbeta1 Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
| Ca_bind_PLCbeta | PLCbeta1 Accession No. : 13 | PLCbeta Pathway No. : 67 | 1 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 1(uM) | - | Substrate Ca PLCbeta Product Ca.PLCbeta |
| 6 Nov 2001 The Kf and Kb values were fixed according to the dose response curves obtained from I.Litosch, Biochem., 2000, 39, 7736-7743. | |||||||