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Molecule Parameter List for IP5-DIPPcmplx | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
| IP5-DIPPcmplx participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction | | No. of occurrences | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | NonOsc_Ca_
IP3metabolism | 31 | Network |
MIPP, CaMKII, CaM,
PKC, IP3-3K, CaRegulation,
Gq, PLCbeta, 134_dephos,
145_dephos, IP4-system, IHP-system,
1345_dephos | | This network models detailed metabolism of Ins(145)P3, integrated with GPCR mediated PLCbeta activation and Ca release by the InsP3 receptor in the neuron. It is similar to the NonOsc_Ca_IP3metab model (accession 23) except that some enzymes have been modified to have reversible kinetics rather than Michaelis-Menten kinetics. These modified enzymes belong to the groups: IP4-system, IP3-3K, 145_dephos and 134_dephos. Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. |
IP5-DIPPcmplx acting as a Molecule in NonOsc_Ca_IP3metabolism Network
IP5-DIPPcmplx acting as a Product in a reaction in NonOsc_Ca_IP3metabolism Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | | IP5-dipp-inhib | NonOsc_Ca_
IP3metabolism
Accession No. : 31 | IHP-system
Pathway No. : 155 | 1
(uM^-1 s^-1) | 1.6
(s^-1) | Kd(bf) = 1.6(uM) | - | Substrate
DIPP1
IP5(13456)
Product
IP5-DIPPcmplx
| | IC50=1.6uM from Safrany et al, EMBO J 17(22); 1998 |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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