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Molecule Parameter List for tot-CaM-CaMKII-PSD

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
tot-CaM-CaMKII-PSD participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1130000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
CaMKII_model363Network
Shared_Object_CaMKII_model3,  CaMKII,  CaM,  
PP1,  PP2B,  PP1_PSD,  
AC,  PKA 
This is the complete model of CaMKII bistability, model 3. It exhibits bistability in CaMKII activation due to autophosphorylation at the PSD and local saturation of PP1. This version of model 3 includes PKA regulatory input. This has little effect on the deterministic calculations, but the PKA pathway introduces a lot of noise which causes a difference in stochastic runs.

tot-CaM-CaMKII-PSD acting as a Molecule in  CaMKII_model3 Network
NameAccession NamePathway NameInitial Conc.
(uM)		Volume
(fL)		Buffered
tot-CaM-CaMKII-PSDCaMKII_model3
Accession No. : 63
  • Shared_Object_
    CaMKII_model3
    Pathway No. : 263
    		• 00.01No

    tot-CaM-CaMKII-PSD acting as a Summed Molecule in      CaMKII_model3 Network
    Accession NamePathway NameTargetInput
    CaMKII_model3
    Accession No. : 63
  • Shared_Object_
    CaMKII_model3
    Pathway No. : 263
    		• tot-CaM-CaMKII-PSD
  • CaMKII-thr286-Ca
    M-PSD
    CaMKII-CaM-PSD

    • tot-CaM-CaMKII-PSD acting as an Enzyme in      CaMKII_model3 Network
     Enzyme Molecule /
    Enzyme Activity    		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1
  • tot-CaM-CaMKII-P
    SD     /
    CaM-act-305-PSD
    		• CaMKII_model3
    Accession No. : 63
  • Shared_Object_
    CaMKII_model3
    Pathway No. : 263
    		• 32064explicit E-S complexSubstrate
  • CaMKII-thr286-PS
    D

    Product
    CaMKII***-PSD
    • 2
  • tot-CaM-CaMKII-P
    SD     /
    CaM-act-286-PSD
    		• CaMKII_model3
    Accession No. : 63
  • Shared_Object_
    CaMKII_model3
    Pathway No. : 263
    		• 319.9960.54explicit E-S complexSubstrate
    CaMKII-CaM-PSD

    Product
  • CaMKII-thr286-Ca
    M-PSD
    • 3
  • tot-CaM-CaMKII-P
    SD     /
    CaM_act_autoph
    		• CaMKII_model3
    Accession No. : 63
  • Shared_Object_
    CaMKII_model3
    Pathway No. : 263
    		• 320.00224explicit E-S complexSubstrate
    CaMKII-PSD

    Product
  • CaMKII-thr286-PS
    D


    • Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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