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Molecule Parameter List for CaM-GEF | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | Ajay_bhalla_
2007_ReacDiff1_
1e-12 | 81 | Network | Shared_Object_Ajay_bhalla_2007_ReacDiff1_1e-12,
PKC, MAPK, Ras, CaM, PKM, chain, kinetics, PKC, MAPK, Ras, CaM, PKM, kinetics[1],
PKC, MAPK, Ras, CaM, PKM, kinetics[2], PKC, MAPK, Ras, CaM, PKM, kinetics[3],
PKC, MAPK, MAPK, Ras, CaM, PKM, kinetics[4], PKC, MAPK, Ras, CaM, PKM,
kinetics[5], PKC, MAPK, Ras, kinetics[6], CaM, PKM, PKC, MAPK, Ras,
CaM, PKM, kinetics[7], PKC, Ras, CaM, PKM, kinetics[8], PKC, MAPK,
Ras, CaM, PKM, kinetics[9], PKC, MAPK, Ras, CaM, PKM, kinetics[10],
PKC, MAPK, Ras, CaM, PKM, kinetics[11], PKC, MAPK, Ras, CaM, PKM, kinetics[12],
PKC, MAPK, Ras, CaM, PKM, kinetics[13], PKC, MAPK, Ras, CaM, PKM, kinetics[14],
PKC, MAPK, Ras, CaM, PKM, kinetics[15], PKC, MAPK, Ras, CaM, PKM, kinetics[16],
PKC, MAPK, Ras, CaM, PKM, kinetics[17], PKC, MAPK, Ras, CaM, PKM, kinetics[18],
PKC, MAPK, Ras, CaM, PKM, kinetics[19], PKC, MAPK, Ras, CaM, PKM, kinetics[20],
PKC, MAPK, Ras, CaM, PKM, kinetics[21], PKC, MAPK, Ras, CaM, PKM, kinetics[22],
PKC, MAPK, Ras, CaM, PKM, kinetics[23], PKC, MAPK, Ras, CaM, PKM | This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-12_Fig4A which was used for the model to replicate Figure 4A from the paper.
This stimulus file pkm_mapk22_diff_1e-12_Fig4G which was used for the model to replicate Figure 4G from the paper |
CaM-GEF acting as a Molecule in Ajay_bhalla_2007_ReacDiff1_1e-12 Network
CaM-GEF acting as an Enzyme in Ajay_bhalla_2007_ReacDiff1_1e-12 Network
| | Enzyme Molecule /
Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | | 1 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 378 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 2 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 385 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 3 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 391 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 4 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 397 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 5 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 404 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 6 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 410 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 7 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 416 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 8 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 422 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 9 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 427 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 10 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 433 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 11 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 439 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 12 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 445 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 13 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 451 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 14 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 457 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 15 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 463 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 16 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 469 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 17 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 475 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 18 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 481 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 19 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 487 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 20 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 493 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 21 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 499 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 22 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 505 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 23 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 511 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 24 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 517 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | | 25 | CaM-GEF /
CaM-GEF-act-ras
| Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 523 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate
GDP-Ras
Product
GTP-Ras
| | | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. |
CaM-GEF acting as a Substrate in a reaction in Ajay_bhalla_2007_ReacDiff1_1e-12 Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
CaM-GEF acting as a Product in a reaction in Ajay_bhalla_2007_ReacDiff1_1e-12 Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| | Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | | 1 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 378 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 2 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 3 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 385 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 4 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 5 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 391 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 6 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 7 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 397 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 8 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 9 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 404 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 10 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 11 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 410 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 12 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 13 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 416 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 14 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 15 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 422 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 16 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 17 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 427 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 18 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 19 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 433 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 20 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 21 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 439 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 22 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 23 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 445 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 24 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 25 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 451 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 26 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 27 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 457 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 28 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 29 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 463 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 30 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 31 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 469 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 32 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 33 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 475 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 34 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 35 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 481 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 36 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 37 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 487 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 38 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 39 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 493 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 40 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 41 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 499 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 42 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 43 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 505 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 44 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 45 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 511 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 46 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 47 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 517 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | | 48 | diff | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Pathway No. : 375 | 0.01
(s^-1) | 0.01
(s^-1) | Keq = 1(uM) | 50sec | Substrate
CaM-GEF
Product
CaM-GEF
| | 49 | CaM-bind-GEF | Ajay_bhalla_
2007_ReacDiff1_
1e-12
Accession No. : 81 | Ras
Pathway No. : 523 | 199.995
(uM^-1 s^-1) | 1
(s^-1) | Kd(bf) = 0.005(uM) | - | Substrate
CaM-Ca4
inact-GEF
Product
CaM-GEF
| | | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
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