Accession Name | Accession No. | Accession Type | Pathway Link |
Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 | 82 | Network | Shared_Object_Ajay_Bhalla_2007_ReacDiff1_1e-13, PKC, MAPK, Ras, CaM, PKM, chain, kinetics, PKC, MAPK, Ras, CaM, PKM, kinetics[1], PKC, MAPK, Ras, CaM, PKM, kinetics[2], PKC, MAPK, Ras, CaM, PKM, kinetics[3], PKC, MAPK, Ras, CaM, PKM, kinetics[4], PKC, MAPK, Ras, CaM, PKM, kinetics[5], PKC, MAPK, Ras, kinetics[6], CaM, PKM, PKC, MAPK, Ras, CaM, PKM, kinetics[7], PKC, MAPK, Ras, CaM, PKM, kinetics[8], PKC, MAPK, Ras, CaM, PKM, kinetics[9], PKC, MAPK, Ras, CaM, PKM, kinetics[10], PKC, MAPK, Ras, CaM, PKM, kinetics[11], PKC, MAPK, Ras, CaM, PKM, kinetics[12], PKC, MAPK, Ras, CaM, PKM, kinetics[13], PKC, MAPK, Ras, CaM, PKM, kinetics[14], PKC, MAPK, Ras, CaM, PKM, kinetics[15], PKC, MAPK, Ras, CaM, PKM, kinetics[16], PKC, MAPK, Ras, CaM, PKM, kinetics[17], PKC, MAPK, Ras, CaM, PKM, kinetics[18], PKC, MAPK, Ras, CaM, PKM, kinetics[19], PKC, MAPK, Ras, CaM, PKM, kinetics[20], PKC, MAPK, Ras, CaM, PKM, kinetics[21], PKC, MAPK, Ras, CaM, PKM, kinetics[22], PKC, MAPK, Ras, CaM, PKM, kinetics[23], PKC, MAPK, Ras, CaM, PKM |
This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.
|
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
1 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
2 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 527 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
3 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
4 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
5 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 534 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
6 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
7 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 552 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
8 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 540 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
9 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
10 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 546 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
11 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
12 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 576 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
13 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
14 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 558 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
15 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
16 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 564 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
17 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
18 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 570 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
19 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
20 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 624 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
21 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
22 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 582 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
23 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
24 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 588 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
25 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
26 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 594 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
27 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
28 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 600 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
29 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
30 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 606 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
31 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
32 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 612 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
33 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
34 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 618 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
35 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
36 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 630 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
37 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
38 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 636 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
39 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
40 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 642 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
41 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
42 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 648 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
43 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
44 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 654 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
45 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
46 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 660 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
47 | diff | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Pathway No. : 526 | 0.001 (s^-1) | 0.001 (s^-1) | Keq = 1(uM) | 500sec | Substrate PKC-Ca
Product PKC-Ca
|
48 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 666 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
49 | PKC-act-by-Ca | Ajay_Bhalla_ 2007_ReacDiff1_ 1e-13 Accession No. : 82 | PKC Pathway No. : 672 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |