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Molecule Parameter List for PKC-DAG-memb*

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

PKC-DAG-memb* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	25	25	0	0	0	24	49

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Ajay_Bhalla_ 2007_ReacDiff3	84	Network	Shared_Object_Ajay_Bhalla_2007_ReacDiff3, PKC, PLA2, MAPK, PLA2, Ras, CaM, chain, kinetics, PKC, MAPK, Ras, CaM, kinetics[1], PKC, PLA2, MAPK, Ras, CaM, kinetics[2], PKC, PLA2, MAPK, Ras, CaM, kinetics[3], PKC, PLA2, MAPK, Ras, CaM, kinetics[4], PKC, PLA2, MAPK, Ras, CaM, kinetics[5], PKC, PLA2, MAPK, Ras, MAPK, CaM, kinetics[6], PKC, PLA2, MAPK, Ras, CaM, kinetics[7], PKC, PLA2, MAPK, Ras, CaM, PKC, kinetics[8], PLA2, MAPK, Ras, CaM, kinetics[9], PKC, PLA2, MAPK, Ras, CaM, kinetics[10], PKC, PLA2, MAPK, Ras, CaM, kinetics[11], PKC, PLA2, MAPK, Ras, CaM, kinetics[12], PKC, PLA2, Ras, CaM, kinetics[13], PKC, PLA2, MAPK, Ras, CaM, kinetics[14], PKC, PLA2, MAPK, Ras, CaM, kinetics[15], PKC, PLA2, MAPK, Ras, kinetics[16], CaM, PKC, PLA2, MAPK, Ras, CaM, kinetics[17], PKC, PLA2, MAPK, Ras, CaM, kinetics[18], PKC, PLA2, MAPK, Ras, CaM, kinetics[19], PKC, PLA2, MAPK, Ras, CaM, kinetics[20], PKC, PLA2, MAPK, Ras, CaM, kinetics[21], PKC, PLA2, MAPK, Ras, CaM, kinetics[22], PKC, PLA2, MAPK, Ras, CaM, kinetics[23], PKC, PLA2, MAPK, Ras, CaM
This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_bistable model. The original single-compartment model is repeated 25 times. In addition, a subset (33 out of 50) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. Here D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) so the kf and kb of this reaction for these 10 micron compartments are both 0.001/sec. The basal calcium level in this model is held at 95 nM which is rather close to threshold for the flip to the active state. This is necessary to sustain active propagation of activation. The stimulus file bis6-propgn_D1e-13_FigEF which was used for the model to replicate Figure 4E and 4F from the paper.

PKC-DAG-memb* acting as a Molecule in Ajay_Bhalla_2007_ReacDiff3 Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	0	125.7	No
PKC-DAG-memb*	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	0	125.7	No

PKC-DAG-memb* acting as a Summed Molecule in Ajay_Bhalla_2007_ReacDiff3 Network

	Accession Nane	Pathway Name	Target	Input
1	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	PKC-active	PKC-DAG-AA* PKC-Ca-memb* PKC-Ca-AA* PKC-DAG-memb* PKC-basal* PKC-AA*

2	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics Pathway No. : 926	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

3	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[1] Pathway No. : 931	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

4	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[2] Pathway No. : 937	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

5	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[3] Pathway No. : 943	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

6	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[4] Pathway No. : 949	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

7	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[5] Pathway No. : 955	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

8	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[6] Pathway No. : 962	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

9	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[7] Pathway No. : 968	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

10	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[8] Pathway No. : 975	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

11	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[9] Pathway No. : 980	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

12	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[10] Pathway No. : 986	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

13	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[11] Pathway No. : 992	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

14	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[12] Pathway No. : 998	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

15	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[13] Pathway No. : 1003	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

16	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[14] Pathway No. : 1009	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

17	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[15] Pathway No. : 1015	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

18	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[16] Pathway No. : 1020	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

19	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[17] Pathway No. : 1027	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

20	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[18] Pathway No. : 1033	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

21	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[19] Pathway No. : 1039	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

22	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[20] Pathway No. : 1045	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

23	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[21] Pathway No. : 1051	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

24	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[22] Pathway No. : 1057	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

25	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[23] Pathway No. : 1063	PKC-active	PKC-DAG-AA* PKC-Ca-AA* PKC-Ca-memb* PKC-DAG-memb* PKC-basal* PKC-AA*

PKC-DAG-memb* acting as a Substrate in a reaction in Ajay_Bhalla_2007_ReacDiff3 Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
2	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
3	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
4	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
5	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
6	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
7	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
8	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
9	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
10	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
11	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
12	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
13	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
14	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
15	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
16	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
17	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
18	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
19	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
20	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
21	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
22	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
23	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
24	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*

PKC-DAG-memb* acting as a Product in a reaction in Ajay_Bhalla_2007_ReacDiff3 Network

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
2	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
3	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
4	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
5	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
6	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
7	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
8	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
9	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
10	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
11	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
12	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
13	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
14	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
15	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
16	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
17	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
18	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
19	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
20	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
21	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
22	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
23	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
24	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
25	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
26	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
27	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
28	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
29	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
30	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
31	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
32	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
33	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
34	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
35	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
36	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
37	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
38	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
39	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
40	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
41	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
42	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
43	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
44	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
45	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
46	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
47	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
48	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-DAG-memb* Product PKC-DAG-memb*
49	PKC-DAG-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
	Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.

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