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Molecule Parameter List for craf-1** | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | Statistics | Accession and Pathway Details | |
Accession Name | Accession No. | Accession Type | Pathway Link | Ajay_Bhalla_ 2007_ReacDiff3 | 84 | Network | Shared_Object_Ajay_Bhalla_2007_ReacDiff3, PKC, PLA2, MAPK, PLA2, Ras, CaM, chain, kinetics, PKC, MAPK, Ras, CaM, kinetics[1], PKC, PLA2, MAPK, Ras, CaM, kinetics[2], PKC, PLA2, MAPK, Ras, CaM, kinetics[3], PKC, PLA2, MAPK, Ras, CaM, kinetics[4], PKC, PLA2, MAPK, Ras, CaM, kinetics[5], PKC, PLA2, MAPK, Ras, MAPK, CaM, kinetics[6], PKC, PLA2, MAPK, Ras, CaM, kinetics[7], PKC, PLA2, MAPK, Ras, CaM, PKC, kinetics[8], PLA2, MAPK, Ras, CaM, kinetics[9], PKC, PLA2, MAPK, Ras, CaM, kinetics[10], PKC, PLA2, MAPK, Ras, CaM, kinetics[11], PKC, PLA2, MAPK, Ras, CaM, kinetics[12], PKC, PLA2, Ras, CaM, kinetics[13], PKC, PLA2, MAPK, Ras, CaM, kinetics[14], PKC, PLA2, MAPK, Ras, CaM, kinetics[15], PKC, PLA2, MAPK, Ras, kinetics[16], CaM, PKC, PLA2, MAPK, Ras, CaM, kinetics[17], PKC, PLA2, MAPK, Ras, CaM, kinetics[18], PKC, PLA2, MAPK, Ras, CaM, kinetics[19], PKC, PLA2, MAPK, Ras, CaM, kinetics[20], PKC, PLA2, MAPK, Ras, CaM, kinetics[21], PKC, PLA2, MAPK, Ras, CaM, kinetics[22], PKC, PLA2, MAPK, Ras, CaM, kinetics[23], PKC, PLA2, MAPK, Ras, CaM | This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_bistable model. The original single-compartment model is repeated 25 times.
In addition, a subset (33 out of 50) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. Here D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) so the kf and kb of this reaction for these 10 micron compartments are both 0.001/sec.
The basal calcium level in this model is held at 95 nM which is rather close to threshold for the flip to the active state. This is necessary to sustain active propagation of activation.
The stimulus file bis6-propgn_D1e-13_FigEF which was used for the model to replicate Figure 4E and 4F from the paper. |
craf-1** acting as a Molecule in Ajay_Bhalla_2007_ReacDiff3 Network
Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 921 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 928 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 934 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 940 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 946 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 952 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 958 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 965 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 971 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 977 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 983 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 989 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 995 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 960 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 1006 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 1012 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 1018 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 1024 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 1030 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 1036 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 1042 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 1048 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 1054 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 1060 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 | craf-1** | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | MAPK Pathway No. : 1066 | 0 | 125.7 | No | Negative feedback by MAPK* by hyperphosphorylating craf-1* gives rise to this pool. Ueki et al JBC 269(22):15756-15761, 1994 |
craf-1** acting as a Substrate for an Enzyme in Ajay_Bhalla_2007_ReacDiff3 Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | 1 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 2 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics Pathway No. : 926 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 3 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[1] Pathway No. : 931 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 4 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[2] Pathway No. : 937 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 5 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[3] Pathway No. : 943 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 6 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[4] Pathway No. : 949 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 7 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[5] Pathway No. : 955 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 8 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[6] Pathway No. : 962 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 9 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[7] Pathway No. : 968 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 10 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[8] Pathway No. : 975 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 11 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[9] Pathway No. : 980 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 12 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[10] Pathway No. : 986 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 13 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[11] Pathway No. : 992 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 14 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[12] Pathway No. : 998 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 15 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[13] Pathway No. : 1003 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 16 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[14] Pathway No. : 1009 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 17 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[15] Pathway No. : 1015 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 18 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[16] Pathway No. : 1020 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 19 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[17] Pathway No. : 1027 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 20 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[18] Pathway No. : 1033 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 21 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[19] Pathway No. : 1039 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 22 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[20] Pathway No. : 1045 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 23 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[21] Pathway No. : 1051 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 24 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[22] Pathway No. : 1057 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. | 25 | PPhosphatase2A / craf**-deph | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[23] Pathway No. : 1063 | 15.6567 | 6 | 4 | explicit E-S complex | Substrate craf-1**
Product craf-1*
| | Ueki et al JBC 269(22) pp 15756-15761 1994 show hyperphosphorylation of craf, so this is there to dephosphorylate it. Identity of phosphatase is not known to me, but it may be PP2A like the rest, so I have made it so. |
craf-1** acting as a Product of an Enzyme in Ajay_Bhalla_2007_ReacDiff3 Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | 1 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 2 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics Pathway No. : 926 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 3 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[1] Pathway No. : 931 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 4 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[2] Pathway No. : 937 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 5 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[3] Pathway No. : 943 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 6 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[4] Pathway No. : 949 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 7 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[5] Pathway No. : 955 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 8 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[6] Pathway No. : 962 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 9 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[7] Pathway No. : 968 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 10 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[8] Pathway No. : 975 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 11 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[9] Pathway No. : 980 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 12 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[10] Pathway No. : 986 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 13 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[11] Pathway No. : 992 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 14 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[12] Pathway No. : 998 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 15 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[13] Pathway No. : 1003 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 16 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[14] Pathway No. : 1009 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 17 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[15] Pathway No. : 1015 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 18 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[16] Pathway No. : 1020 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 19 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[17] Pathway No. : 1027 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 20 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[18] Pathway No. : 1033 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 21 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[19] Pathway No. : 1039 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 22 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[20] Pathway No. : 1045 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 23 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[21] Pathway No. : 1051 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 24 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[22] Pathway No. : 1057 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. | 25 | MAPK* / MAPK*-feedback | Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84 | kinetics[23] Pathway No. : 1063 | 25.6405 | 10 | 4 | explicit E-S complex | Substrate craf-1*
Product craf-1**
| | Ueki et al JBC 269(22):15756-15761 show the presence of this step, but not the rate consts, which are derived from Sanghera et al JBC 265(1):52-57, 1990, see the deriv in the MAPK* notes. |
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