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Molecule Parameter List for APC

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

*APC* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	25	0	0	125	0	0	25

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Ajay_Bhalla_ 2007_ReacDiff3	84	Network	Shared_Object_Ajay_Bhalla_2007_ReacDiff3, PKC, PLA2, MAPK, PLA2, Ras, CaM, chain, kinetics, PKC, MAPK, Ras, CaM, kinetics[1], PKC, PLA2, MAPK, Ras, CaM, kinetics[2], PKC, PLA2, MAPK, Ras, CaM, kinetics[3], PKC, PLA2, MAPK, Ras, CaM, kinetics[4], PKC, PLA2, MAPK, Ras, CaM, kinetics[5], PKC, PLA2, MAPK, Ras, MAPK, CaM, kinetics[6], PKC, PLA2, MAPK, Ras, CaM, kinetics[7], PKC, PLA2, MAPK, Ras, CaM, PKC, kinetics[8], PLA2, MAPK, Ras, CaM, kinetics[9], PKC, PLA2, MAPK, Ras, CaM, kinetics[10], PKC, PLA2, MAPK, Ras, CaM, kinetics[11], PKC, PLA2, MAPK, Ras, CaM, kinetics[12], PKC, PLA2, Ras, CaM, kinetics[13], PKC, PLA2, MAPK, Ras, CaM, kinetics[14], PKC, PLA2, MAPK, Ras, CaM, kinetics[15], PKC, PLA2, MAPK, Ras, kinetics[16], CaM, PKC, PLA2, MAPK, Ras, CaM, kinetics[17], PKC, PLA2, MAPK, Ras, CaM, kinetics[18], PKC, PLA2, MAPK, Ras, CaM, kinetics[19], PKC, PLA2, MAPK, Ras, CaM, kinetics[20], PKC, PLA2, MAPK, Ras, CaM, kinetics[21], PKC, PLA2, MAPK, Ras, CaM, kinetics[22], PKC, PLA2, MAPK, Ras, CaM, kinetics[23], PKC, PLA2, MAPK, Ras, CaM
This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_bistable model. The original single-compartment model is repeated 25 times. In addition, a subset (33 out of 50) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. Here D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) so the kf and kb of this reaction for these 10 micron compartments are both 0.001/sec. The basal calcium level in this model is held at 95 nM which is rather close to threshold for the flip to the active state. This is necessary to sustain active propagation of activation. The stimulus file bis6-propgn_D1e-13_FigEF which was used for the model to replicate Figure 4E and 4F from the paper.

APC acting as a Molecule in Ajay_Bhalla_2007_ReacDiff3 Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 920	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 922	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 933	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 939	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 945	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 951	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 957	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 964	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 970	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 976	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 982	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 988	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 994	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1000	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1005	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1011	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1017	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1023	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1029	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1035	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1041	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1047	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1053	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1059	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.
APC	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1065	30.0003	125.7	Yes
arachodonylphosphatidylcholine is the favoured substrate from Wijkander and Sundler, JBC 202 pp 873-880, 1991. Their assay used 30 uM substrate, which is what the kinetics in this model are based on. For the later model we should locate a more realistic value for APC.

APC acting as a Substrate for an Enzyme in Ajay_Bhalla_2007_ReacDiff3 Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 920	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
2	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 920	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
3	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 920	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
4	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 920	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
5	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 920	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
6	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 922	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
7	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 922	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
8	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 922	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
9	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 922	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
10	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 922	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
11	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 933	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
12	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 933	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
13	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 933	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
14	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 933	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
15	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 933	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
16	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 939	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
17	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 939	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
18	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 939	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
19	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 939	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
20	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 939	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
21	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 945	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
22	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 945	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
23	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 945	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
24	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 945	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
25	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 945	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
26	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 951	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
27	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 951	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
28	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 951	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
29	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 951	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
30	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 951	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
31	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 957	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
32	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 957	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
33	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 957	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
34	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 957	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
35	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 957	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
36	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 964	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
37	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 964	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
38	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 964	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
39	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 964	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
40	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 964	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
41	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 970	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
42	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 970	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
43	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 970	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
44	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 970	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
45	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 970	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
46	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 976	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
47	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 976	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
48	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 976	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
49	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 976	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
50	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 976	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
51	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 982	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
52	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 982	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
53	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 982	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
54	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 982	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
55	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 982	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
56	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 988	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
57	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 988	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
58	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 988	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
59	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 988	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
60	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 988	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
61	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 994	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
62	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 994	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
63	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 994	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
64	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 994	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
65	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 994	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
66	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1000	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
67	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1000	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
68	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1000	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
69	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1000	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
70	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1000	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
71	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1005	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
72	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1005	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
73	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1005	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
74	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1005	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
75	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1005	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
76	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1011	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
77	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1011	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
78	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1011	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
79	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1011	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
80	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1011	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
81	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1017	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
82	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1017	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
83	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1017	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
84	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1017	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
85	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1017	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
86	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1023	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
87	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1023	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
88	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1023	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
89	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1023	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
90	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1023	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
91	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1029	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
92	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1029	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
93	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1029	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
94	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1029	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
95	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1029	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
96	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1035	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
97	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1035	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
98	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1035	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
99	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1035	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
100	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1035	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
101	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1041	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
102	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1041	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
103	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1041	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
104	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1041	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
105	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1041	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
106	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1047	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
107	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1047	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
108	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1047	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
109	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1047	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
110	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1047	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
111	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1053	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
112	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1053	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
113	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1053	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
114	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1053	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
115	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1053	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
116	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1059	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
117	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1059	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
118	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1059	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
119	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1059	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
120	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1059	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
121	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1065	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
122	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1065	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
123	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1065	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
124	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1065	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
125	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1065	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*

APC acting as a Product in a reaction in Ajay_Bhalla_2007_ReacDiff3 Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 920	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
2	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 922	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
3	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 933	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
4	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 939	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
5	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 945	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
6	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 951	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
7	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 957	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
8	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 964	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
9	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 970	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
10	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 976	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
11	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 982	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
12	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 988	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
13	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 994	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
14	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1000	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
15	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1005	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
16	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1011	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
17	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1017	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
18	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1023	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
19	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1029	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
20	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1035	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
21	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1041	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
22	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1047	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
23	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1053	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
24	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1059	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
25	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1065	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17

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