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Molecule List for pathway CaMKII (Pathway Number 235) in Accession AMPAR_traff_model0 (Accession Number 59) |
Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.  arrow indicates that ordering is done according to ascending or descending order.The entries are grouped according to Pathway Number and are alternately color coded using  and  color. |
| Name | Accession Type | Initial Conc. (uM) | Volume (fL) | Buffered | Sum Total Of | |||
| 1 | PSD_control | Network | 2 | 0.01 | Yes | - | ||
| 2 | cyt | Network | 2 | 0.09 | Yes | - | ||
| 3 | M-PSD | Network | 0 | 0.01 | No | - | ||
| 4 | 286P-PSD | Network | 0 | 0.01 | No | M-PSD D | ||
| 5 | SD | Network | 0 | 0.01 | No | M-PSD CaMKII-CaM-PSD | ||
| 6 | actCaMKII-PSD | Network | 2 | 0.01 | No | M-PSD CaMKII-CaM-PSD tot-auto-PSD | ||
| 7 | tot_CaMKII_PSD | Network | 2 | 0.01 | No | actCaMKII-PSD CaMKII-PSD D | ||
| 8 | tot-auto-PSD | Network | 2 | 0.01 | No | D CaMKII***-PSD PSD | ||
| 9 | act_CaMKII_cyt | Network | 2 | 0.09 | No | tot_CaM_CaMKII CaMKII | ||
| 10 | tot_CaMKII_cyt | Network | 22 | 0.09 | No | CaMKII-CaM aM CaMKII-thr286 CaMKII*** CaMK-thr305 CaMKII cyt | ||
| 11 | CaMKII | Network | 2 | 0.09 | No | CaMKII-thr286 CaMKII*** cyt | ||
| 12 | tot_CaM_CaMKII | Network | 0 | 0.09 | No | CaMKII-CaM aM | ||
| 13 | PSD | Network | 2 | 0.01 | No | - | ||
| 14 | CaMKII | Network | 20 | 0.09 | No | - | ||
| Huge conc of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. This comes to about 70 uM. | ||||||||
| 15 | CaMKII-CaM-PSD | Network | 0 | 0.01 | No | - | ||
| 16 | D | Network | 0 | 0.01 | No | - | ||
| 17 | NMDAR | Network | 120 | 0.01 | No | - | ||
| The stochiometry is a bit off here. Each NMDAR actually binds to a holoenzyme, about 12 CaMKII subunits. But our CaMKII calculations are in terms of individual subunits. So as a hack, we put in much more NMDAR than is actually there. | ||||||||
| 18 | CaMKII-PSD | Network | 0 | 0.01 | No | - | ||
| 19 | CaMKII***-PSD | Network | 0 | 0.01 | No | - | ||
| 20 | D | Network | 0 | 0.01 | No | - | ||