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Enzyme List for pathway PP2B (Pathway Number 285) in Accession AMPAR_CaMKII_weak_coupling (Accession Number 65)

Entries are grouped according to Pathway Number and they are alternately color coded using  and   color.
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  Enzyme Molecule /

 Enzyme Activity
Pathway Name / 
Pathway No.
Km
(uM)
kcat
(s^-1)
Ratio
(k2/k3)
Enzyme TypeReagents
1 CaM_Ca_n-CaNAB /
PP2B[9]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A845*_B831*845*
Product : 
A845*_B831*
2 CaM_Ca_n-CaNAB /
PP2B
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A845*_B845*
Product : 
A_B845*
3 CaM_Ca_n-CaNAB /
PP2B[1]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A845*_B845*
Product : 
A845*_B
4 CaM_Ca_n-CaNAB /
PP2B[2]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A_B845*
Product : 
A_B
5 CaM_Ca_n-CaNAB /
PP2B[3]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A845*_B
Product : 
A_B
6 CaM_Ca_n-CaNAB /
PP2B[4]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A831*845*_B845*
Product : 
A831*_B845*
7 CaM_Ca_n-CaNAB /
PP2B[5]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A831*845*_B845*
Product : 
A831*845*_B
8 CaM_Ca_n-CaNAB /
PP2B[6]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A831*_B845*
Product : 
A831*_B
9 CaM_Ca_n-CaNAB /
PP2B[7]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A831*845*_B
Product : 
A831*_B
10 CaM_Ca_n-CaNAB /
PP2B[8]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A845*_B831*845*
Product : 
A_B831*845*
11 CaM_Ca_n-CaNAB /
PP2B[32]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A835*845*_
B835*845*

Product : 
A831*845*_B831*
12 CaM_Ca_n-CaNAB /
PP2B[10]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A_B831*845*
Product : 
A_B831*
13 CaM_Ca_n-CaNAB /
PP2B[11]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A845*_B831*
Product : 
A_B831*
14 CaM_Ca_n-CaNAB /
PP2B[12]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A835*845*_
B835*845*

Product : 
A831*_B831*845*
15 CaM_Ca_n-CaNAB /
PP2B[13]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A835*845*_
B835*845*

Product : 
A831*845*_B831*
16 CaM_Ca_n-CaNAB /
PP2B[14]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A831*845*_B831*
Product : 
A831*_B831*
17 CaM_Ca_n-CaNAB /
PP2B[15]
PP2B

Pathway No. 285
4.9706124explicit E-S complexSubstrate: 
A831*_B831*845*
Product : 
A831*_B831*
18 CaNAB-Ca4 /
  • dephosph_
    inhib1_noCaM
  • PP2B

    Pathway No. 285
    4.970790.0344explicit E-S complexSubstrate: 
    I1*
    Product : 
    I1
      The rates here are so slow I do not know if we should even bother with this enz reacn. These numbers are from Liu and Storm. Other refs suggest that the Km stays the same but the Vmax goes to 10% of the CaM stim levels. Prev: k1=2.2e-9, k2 = 0.0052, k3 = 0.0013 New : k1=5.7e-8, k2=.136, k3=.034
    19 CaNAB-Ca4 /
  • dephosph_
    inhib1_noCaM_
    PSD
  • PP2B

    Pathway No. 285
    4.970710.0344explicit E-S complexSubstrate: 
    I1*
    Product : 
    I1
      The rates here are so slow I do not know if we should even bother with this enz reacn. These numbers are from Liu and Storm. Other refs suggest that the Km stays the same but the Vmax goes to 10% of the CaM stim levels. Prev: k1=2.2e-9, k2 = 0.0052, k3 = 0.0013 New : k1=5.7e-8, k2=.136, k3=.034
    20 CaM_Ca_n-CaNAB /
    PP2B[22]
    PP2B

    Pathway No. 285
    4.9706124explicit E-S complexSubstrate: 
    A831*_B845*
    Product : 
    A831*_B

     
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