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Enzyme List for pathway PP2B (Pathway Number 285) in Accession AMPAR_CaMKII_weak_coupling (Accession Number 65)

Entries are grouped according to Pathway Number and they are alternately color coded using

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	Enzyme Molecule / Enzyme Activity	Pathway Name / Pathway No.	Km (uM)	kcat (s^-1)	Ratio (k2/k3)	Enzyme Type	Reagents
1	CaNAB-Ca4 / dephosph_ inhib1_noCaM_ PSD	PP2B Pathway No. 285	4.97071	0.034	4	explicit E-S complex	Substrate: I1* Product : I1
	The rates here are so slow I do not know if we should even bother with this enz reacn. These numbers are from Liu and Storm. Other refs suggest that the Km stays the same but the Vmax goes to 10% of the CaM stim levels. Prev: k1=2.2e-9, k2 = 0.0052, k3 = 0.0013 New : k1=5.7e-8, k2=.136, k3=.034
2	CaNAB-Ca4 / dephosph_ inhib1_noCaM	PP2B Pathway No. 285	4.97079	0.034	4	explicit E-S complex	Substrate: I1* Product : I1
	The rates here are so slow I do not know if we should even bother with this enz reacn. These numbers are from Liu and Storm. Other refs suggest that the Km stays the same but the Vmax goes to 10% of the CaM stim levels. Prev: k1=2.2e-9, k2 = 0.0052, k3 = 0.0013 New : k1=5.7e-8, k2=.136, k3=.034
3	CaM_Ca_n-CaNAB / PP2B	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A845_B845 Product : A_B845*
4	CaM_Ca_n-CaNAB / PP2B[32]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A835845_ B835845 Product : A831845_B831*
5	CaM_Ca_n-CaNAB / PP2B[1]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A845_B845 Product : A845*_B
6	CaM_Ca_n-CaNAB / PP2B[2]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A_B845* Product : A_B
7	CaM_Ca_n-CaNAB / PP2B[3]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A845_B Product :* A_B
8	CaM_Ca_n-CaNAB / PP2B[4]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A831845_B845* Product : A831_B845
9	CaM_Ca_n-CaNAB / PP2B[5]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A831845_B845* Product : A831845_B
10	CaM_Ca_n-CaNAB / PP2B[6]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A831_B845 Product : A831*_B
11	CaM_Ca_n-CaNAB / PP2B[7]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A831845_B Product : A831*_B
12	CaM_Ca_n-CaNAB / PP2B[8]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A845_B831845* Product : A_B831845
13	CaM_Ca_n-CaNAB / PP2B[9]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A845_B831845* Product : A845_B831
14	CaM_Ca_n-CaNAB / PP2B[10]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A_B831845 Product : A_B831*
15	CaM_Ca_n-CaNAB / PP2B[11]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A845_B831 Product : A_B831*
16	CaM_Ca_n-CaNAB / PP2B[12]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A835845_ B835845 Product : A831_B831845*
17	CaM_Ca_n-CaNAB / PP2B[13]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A835845_ B835845 Product : A831845_B831*
18	CaM_Ca_n-CaNAB / PP2B[14]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A831845_B831* Product : A831_B831
19	CaM_Ca_n-CaNAB / PP2B[15]	PP2B Pathway No. 285	4.97061	2	4	explicit E-S complex	Substrate: A831_B831845* Product : A831_B831
20	CaM_Ca_n-CaNAB / dephosph_ neurogranin_PSD	PP2B Pathway No. 285	10.012	0.67	3.98507	explicit E-S complex	Substrate: neurogranin_ PSD Product :* neurogranin_PSD
	From Seki et al ABB 316(2):673-679