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Accession Type:
Network
fig3_CaMKII
Shared_Object_
fig3_CaMKII
CaMKII
CaM
PP1
PP2B
 Molecule
 Reaction
PKA
AC

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Reaction List for pathway PP2B (Pathway Number 16)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 Ca-bind-CaNAB10008
(uM^-2 s^-1)		1
(s^-1)		Kd(af) = 0.01(uM)-CaNAB
Ca
Ca
CaNAB-Ca2
2 Ca-bind-CaNAB-Ca
2		3.6
(uM^-2 s^-1)		1
(s^-1)		Kd(af) = 0.527(uM)-Ca
Ca
CaNAB-Ca2
CaNAB-Ca4
3 CaM-Ca2-bind-CaN
AB		0.24
(uM^-1 s^-1)		1
(s^-1)		Kd(bf) = 4.1667(uM)-CaNAB-Ca4
CaM-TR2-Ca2
CaMCa2-CANAB
4 CaMCa3-bind-CaNA
B		2.238
(uM^-1 s^-1)		1
(s^-1)		Kd(bf) = 0.4468(uM)-CaM-Ca3
CaNAB-Ca4
CaMCa3-CaNAB
5 CaMCa4-bind-CaNA
B		600
(uM^-1 s^-1)		1
(s^-1)		Kd(bf) = 0.0017(uM)-CaM-Ca4
CaNAB-Ca4
CaMCa4-CaNAB


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Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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