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Accession Type:
Network
MAPK_network_
2003
Shared_Object_
MAPK_network_
2003
PKC
PLA2
PLCbeta
Gq
MAPK
Ras
EGFR
Sos
PLC_g
CaMKII
 Molecule
 Enzyme
 Reaction
CaM
PP1
PP2B
PKA
AC

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Parameters for CaMKII (Pathway Number 216)

Pathway Layout

Pathway Basic Parameters

Pathway NameCaMKII
Pathway Entry Number 216
Accession Number 50
Accession Name MAPK_network_2003
Species Generic mammalian
Tissue Brain - Neuronal
CellCompartmentSynapse
Related Pathways 13, 26, 80, 106, 121, 145, 159, 174, 202, 235, 245, 258, 264, 272, 282, 322, 339, 357
Notes Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.

Statistics

8
4
3

Conversion format

FormatFile
Native Format (GENESIS format)    path216.g   
GENESIS Format (Annotated version)    Anno_path216.g   
MATLAB format    path216.m   


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Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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