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Molecule List for pathway MAPK (Pathway Number 139) in Accession MAPK_osc (Accession Number 27)

Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.
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The entries are grouped according to Pathway Number and are alternately color coded using  and  color.
  NameAccession
Type
Initial
Conc.

(uM)
Volume
(fL)
BufferedSum Total Of
1 
  • inactiveRas-MKKK
  • Pathway00.0016667No
        This is the inactive form of Ras-MKKK. Based on the reaction scheme from Kholodenko 2000, this is equivalent to a binding of the MAPK-PP to the Ras. The amount of Ras in the model is small enough that negligible amounts of MAPK are involved in this reaction. So it is a fair approximation to the negative feedback mechanism from Kholodenko, 2000.
    2 int1Pathway0.0010.0016667No
        This is the intermediate enzyme which catalyses the dephosphorylation of MKKK-P to MKKK. The concentration is set to 1 nM based on from Kholodenko, 2000
    3 int2Pathway0.0010.0016667No
        This intermediate enzyme which catalyses the dephosphorylation of MKK-PP to MKK-P. The concentration is 1nM. from Kholodenko, 2000
    4 int3Pathway0.0010.0016667No
        This intermediate enzyme catalyses the dephosphorylation of MKK-P to MKK. The concentration is 1nM from Kholodenko, 2000
    5 int4Pathway0.0010.0016667No
        This intermediate enzyme catalyses the dephosphorylation of MAPK-PP to MAPK-P. The concentration is 1nM. from Kholodenko, 2000
    6 int5Pathway0.0010.0016667No
        This catalyses the conversion of MAPK-P to MAPK. The concenration is 1nM. from Kholodenko, 2000
    7 MAPKPathway0.30.0016667No
        The total concn. of MAPK is 300nM from Kholodenko, 2000.
    8 MAPK-PPathway00.0016667No
        This is the single phopshorylated form of MAPK from Kholodenko, 2000.
    9 MAPK-PPPathway00.0016667No
        This is the double phosphorylated and active form of MAPK. from Kholodenko, 2000.
    10 MKKPathway0.30.0016667No
        The total concn. of MKK is 300nM from Kholodenko,2000
    11 MKK-PPathway00.0016667No
        This is the single phoshorylated form of MKK. from Kholodenko, 2000.
    12 MKK-PPPathway00.0016667No
        This is the double phosphorylated and active form of MKK from Kholodenko, 2000
    13 MKKKPathway0.10.0016667No
        The total concn. of MKKK is 100nM from Kholodenko, 2000
    14 MKKK-PPathway00.0016667No
        This is the phosphorylated form of MKKK which converts MKK to MKK-P and then to MKK-PP from Kholodenko, 2000.
    15 Ras-MKKKKPathway0.0010.0016667No
        The concn. of Ras-MKKKK* is set to 1 nM implicitly from Kholodenko, 2000

     
    Result: 1 - 15 of 15 rows are displayed



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