NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By


 
Result: 1 - 7 of 7 rows are displayed

Reaction List for pathway MAPK (Pathway Number 193) in Accession MAPK_Asthagiri_adapt_fb (Accession Number 45)

Entries are grouped according to Pathway Number and they are alternately color coded using  and  color.
Further ordering can be done to the table header.  indicates that ordering is done according to ascending or descending order.
Keq is calculated only for first order reactions.
Kd is calculated only for second order reactions. [nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules]
  Reaction
Name
Pathway Name / 
Pathway No.
KfKbKdtauReagents
1 L-bind-RMAPK

Pathway No. 193
0.1666
(uM^-1 s^-1)
0.005
(s^-1)
Kd(bf) = 0.03(uM)-  Substrate:
 L
 R

 Products:
 C
  Kf = 10^7/M-1 min-1 and Kr is 0.3 min-1 from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
2 C-dimerMAPK

Pathway No. 193
1
(uM^-1 s^-1)
1
(s^-1)
Keq = 1(uM)-  Substrate:
 C
 C

 Products:
 C2
  Kc is 6*10^7 M-1 min-1 and Ku is 60 min-1 from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
3 C2-phosMAPK

Pathway No. 193
0.833
(s^-1)
0.0833
(s^-1)
Keq = 0.1(uM)1.091sec  Substrate:
 C2

 Products:
 C*
  Kc+ is 50min-1 and Kc- is 5min-1 from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
4 C*-bind-A1MAPK

Pathway No. 193
5.0001
(uM^-1 s^-1)
0.5
(s^-1)
Kd(bf) = 0.1(uM)-  Substrate:
 C*
 A1

 Products:
 C*A1
  Kf1 is 3*10^8 M-1 min-1 and Kr1 is 0.5/sec from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
5 C*A1-bind-A2MAPK

Pathway No. 193
5.0001
(uM^-1 s^-1)
0.5
(s^-1)
Kd(bf) = 0.1(uM)-  Substrate:
 C*A1
 A2

 Products:
 E0*
  kf2 and kr2 are 3*10^8 M-1 min-1 and 0.5/sec from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
6 A1-bind-A2MAPK

Pathway No. 193
5.0001
(uM^-1 s^-1)
0.5
(s^-1)
Kd(bf) = 0.1(uM)-  Substrate:
 A2
 A1

 Products:
 A1A2
  Kc12 and Kd12 are 3*10^8 M-1 min-1 and 0.5/sec from Asthagiri and Lauffenburger 2001.
7 C*-bind-A1A2MAPK

Pathway No. 193
5.0001
(uM^-1 s^-1)
0.5
(s^-1)
Kd(bf) = 0.1(uM)-  Substrate:
 A1A2
 C*

 Products:
 E0*
  Kf12 and Kr12 are 3*10^8 M-1 min-1 and 0.5/sec from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39

 
Result: 1 - 7 of 7 rows are displayed



Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.