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Accession Type:
Network
fig3_CaMKII
Shared_Object_
fig3_CaMKII
 Molecule
 Enzyme
CaMKII
CaM
PP1
PP2B
PKA
AC

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Enzyme List for pathway Shared_Object_fig3_CaMKII (Pathway Number 12)

 Molecule Name/
Site Name 		Km (uM) kcat (1/s)Ratio
(k2/k3)		Enzyme TypeSubstrate Product
1 Enzyme Activity:
Deph-thr286

Enzyme Molecule:
PP1-active		5.099070.354explicit E-S complex
  • CaMKII-thr286*-C
    aM
    		• CaMKII-CaM
    2 Enzyme Activity:
    Deph-thr286c

    Enzyme Molecule:
    PP1-active    		5.099070.354explicit E-S complexCaMKII***
    		CaMK-thr306
    3 Enzyme Activity:
    Deph-thr305

    Enzyme Molecule:
    PP1-active    		5.099070.354explicit E-S complexCaMKII***
    		CaMKII-thr286
    4 Enzyme Activity:
    Deph-thr306

    Enzyme Molecule:
    PP1-active    		5.099070.354explicit E-S complexCaMK-thr306
    		CaMKII
    5 Enzyme Activity:
    dephosph-PP1-I*

    Enzyme Molecule:
    CaM(Ca)n-CaNAB    		4.970760.344explicit E-S complexPP1-I1*
    		PP1-I1
    6 Enzyme Activity:
    dephosph_inhib1

    Enzyme Molecule:
    CaM(Ca)n-CaNAB    		4.970760.344explicit E-S complexI1*
    		I1
    7 Enzyme Activity:
    dephosph_
    inhib1_noCaM

    Enzyme Molecule:
    CaNAB-Ca4    		4.970760.0344explicit E-S complexI1*
    		I1
    8 Enzyme Activity:
    dephosph_
    neurogranin

    Enzyme Molecule:
    CaM(Ca)n-CaNAB    		10.0120.673.98507explicit E-S complexneurogranin*
    		neurogranin
    9 Enzyme Activity:
    Deph_thr286b

    Enzyme Molecule:
    PP1-active    		5.099070.354explicit E-S complexCaMKII-thr286
    		CaMKII
    10 Enzyme Activity:
    phosph-AC2

    Enzyme Molecule:
    PKC-active    		33.333344explicit E-S complexAC2
    		AC2*
    11 Enzyme Activity:
    phosph-PDE

    Enzyme Molecule:
    PKA-active    		7.594explicit E-S complexcAMP-PDE
    		cAMP-PDE*
    12 Enzyme Activity:
    PKA-phosph-I1

    Enzyme Molecule:
    PKA-active    		7.594explicit E-S complexI1
    		I1*
    13 Enzyme Activity:
    PKC-phosph-neuro
    granin

    Enzyme Molecule:
    PKC-active    		28.62750.584.03448explicit E-S complexneurogranin
    		neurogranin*
    14 Enzyme Activity:
    PKC-phosph-ng-Ca
    M

    Enzyme Molecule:
    PKC-active    		28.59480.354explicit E-S complexneurogranin-CaM
    		CaM
    neurogranin*
    15 Enzyme Activity:
    PP2A-dephosph-I1

    Enzyme Molecule:
    PP2A    		7.8282864.16667explicit E-S complexI1*
    		I1
    16 Enzyme Activity:
    PP2A-dephosph-PP
    1-I*

    Enzyme Molecule:
    PP2A    		7.8282864.16667explicit E-S complexPP1-I1*
    		PP1-I1


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