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Accession Type:
Network

fig4_synapse

		Shared_Object_ fig4_synapse
		Molecule
		Enzyme
		Reaction

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Molecule List for pathway Shared_Object_fig4_synapse (Pathway Number 19)

	Name	Initial Conc. (uM)	Volume (fL)	Buffered
1	AA	0	1000	No

2	BetaGamma	0	1000	No

3	Ca	0.08	1000	No

4	CaM(Ca)n-CaNAB	0	1000	No

5	CaM-Ca3	0	1000	No

6	CaM-Ca4	0	1000	No

7	CaM-TR2-Ca2	0	1000	No

8	CaMKII-act	0	1000	No

9	cAMP	0	1000	No

10	CaN-active	0	1000	No

11	CaNAB-Ca4	0	1000	No

12	DAG	0	1000	No

13	G*GDP	0	1000	No

14	G*GTP	0	1000	No

15	Glu	0	1000	No

16	Gs-alpha	0	1000	No

17	IP3	0	1000	No

18	MAPK*	0	1000	No

19	MKP-1	0.0032	1000	No

20	PIP2	2.5	1000	Yes

21	PKA-active	0	1000	No

22	PKC-active	0.02	1000	No

23	PP1-active	1.8	1000	No

24	PP2A	0.12	1000	No

25	PPhosphatase2A	0.224	1000	No

26	synapse	0	1000	No

27	temp-PIP2	2.5	1000	Yes

28	tot_PP1-act	0	1000	No
	tot_PP1 has inputs from Deph-thr286, PP1-active, Deph-thr305, Deph-thr286c, Deph-thr286b,Deph-thr305. except PP1-active all other inputs are enzyme-substrate complex which is not currently supported by doqcs. But can be accessed from GENESIS file.

Summed Molecule List

	Target	Inputs
1	Ca	-
2	CaM(Ca)n-CaNAB	CaMCa4-CaNAB CaMCa3-CaNAB CaMCa2-CANAB
3	CaMKII-act	tot_CaM_CaMKII tot_autonomous_ CaMKII
4	CaN-active	CaM(Ca)n-CaNAB CaNAB-Ca4
5	PKC-active	PKC-DAG-AA* PKC-Ca-memb* PKC-Ca-AA* PKC-DAG-memb* PKC-basal* PKC-AA*
6	tot_PP1-act	PP1-active
tot_PP1 has inputs from Deph-thr286, PP1-active, Deph-thr305, Deph-thr286c, Deph-thr286b,Deph-thr305. except PP1-active all other inputs are enzyme-substrate complex which is not currently supported by doqcs. But can be accessed from GENESIS file.

Pathway Details Molecule List Enzyme List Reaction List

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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