 |  |  CaRegulation |
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Enzyme List for pathway IP3-3K (Pathway Number 162) | | Molecule Name/
Site Name | Km (uM) | kcat (1/s) | Ratio
(k2/k3) | Enzyme Type | Substrate | Product |
| 1 |
Enzyme Activity:
ip3-3k
Enzyme Molecule:
IP3_3K | 1.40001 | 3.0475 | 4 | explicit E-S complex | IP3(145)
| IP4(1345)
| | | from Johanson et al, JBC 263; 1988 Original Vmax scaled up by 50% to obtain value at 37C, as enzyme assay was done at 30C Km increased from 0.2 to 1.4 as per various other reports (Shears Review, BiochemJ 260; 1989) |
| 2 |
Enzyme Activity:
ip3-3k*
Enzyme Molecule:
IP3_3K* | 1.40001 | 3.0475 | 4 | explicit E-S complex | IP3(145)
| IP4(1345)
| | | from Communi et al, EMBO J 16; 1997 In absence of CaM binding, activity same as that of non-phosphorylated enzyme |
| 3 |
Enzyme Activity:
ip3-3k*1
Enzyme Molecule:
IP3_3K*1 | 1.40004 | 0.76187 | 4.00003 | explicit E-S complex | IP3(145)
| IP4(1345)
| | | from Sim et al, JBC 265; 1990 |
Pathway Details Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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