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Pathway List for cam

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Entries are color tagged depending on Network  or Pathway 
#137#137#137#137#137#137#137#137#137#137#137#137#137#137#137#137#137#137#137#137
  Pathway Name
Pathway No.
Accession Name
Accession No.
Accession
Type
Pathway statisticscam statisticsSource
Entry Date
61 CaM
Pathway No. 615
 Ajay_Bhalla_
2007_ReacDiff1_
1e-13

Accession No. 82
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609621627633639645651657663669675681688
695701706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.
   
This pathway is part of accession 82 and is completely specified in the file acc82.g.
There is no separate for just this pathway.
FormatFile
62 CaM
Pathway No. 621
 Ajay_Bhalla_
2007_ReacDiff1_
1e-13

Accession No. 82
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615627633639645651657663669675681688
695701706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.
   
This pathway is part of accession 82 and is completely specified in the file acc82.g.
There is no separate for just this pathway.
FormatFile
63 CaM
Pathway No. 627
 Ajay_Bhalla_
2007_ReacDiff1_
1e-13

Accession No. 82
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621633639645651657663669675681688
695701706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.
   
This pathway is part of accession 82 and is completely specified in the file acc82.g.
There is no separate for just this pathway.
FormatFile
64 CaM
Pathway No. 633
 Ajay_Bhalla_
2007_ReacDiff1_
1e-13

Accession No. 82
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627639645651657663669675681688
695701706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.
   
This pathway is part of accession 82 and is completely specified in the file acc82.g.
There is no separate for just this pathway.
FormatFile
65 CaM
Pathway No. 639
 Ajay_Bhalla_
2007_ReacDiff1_
1e-13

Accession No. 82
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633645651657663669675681688
695701706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.
   
This pathway is part of accession 82 and is completely specified in the file acc82.g.
There is no separate for just this pathway.
FormatFile
66 CaM
Pathway No. 645
 Ajay_Bhalla_
2007_ReacDiff1_
1e-13

Accession No. 82
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639651657663669675681688
695701706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.
   
This pathway is part of accession 82 and is completely specified in the file acc82.g.
There is no separate for just this pathway.
FormatFile
67 CaM
Pathway No. 651
 Ajay_Bhalla_
2007_ReacDiff1_
1e-13

Accession No. 82
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639645657663669675681688
695701706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.
   
This pathway is part of accession 82 and is completely specified in the file acc82.g.
There is no separate for just this pathway.
FormatFile
68 CaM
Pathway No. 657
 Ajay_Bhalla_
2007_ReacDiff1_
1e-13

Accession No. 82
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639645651663669675681688
695701706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.
   
This pathway is part of accession 82 and is completely specified in the file acc82.g.
There is no separate for just this pathway.
FormatFile
69 CaM
Pathway No. 663
 Ajay_Bhalla_
2007_ReacDiff1_
1e-13

Accession No. 82
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639645651657669675681688
695701706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.
   
This pathway is part of accession 82 and is completely specified in the file acc82.g.
There is no separate for just this pathway.
FormatFile
70 CaM
Pathway No. 669
 Ajay_Bhalla_
2007_ReacDiff1_
1e-13

Accession No. 82
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639645651657663675681688
695701706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.
   
This pathway is part of accession 82 and is completely specified in the file acc82.g.
There is no separate for just this pathway.
FormatFile
71 CaM
Pathway No. 675
 Ajay_Bhalla_
2007_ReacDiff1_
1e-13

Accession No. 82
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639645651657663669681688
695701706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.
   
This pathway is part of accession 82 and is completely specified in the file acc82.g.
There is no separate for just this pathway.
FormatFile
72 CaM
Pathway No. 681
 Ajay_Bhalla_
2007_ReacDiff2

Accession No. 83
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639645651657663669675688
695701706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 40-compartment reaction-diffusion-transport version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 40 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec In addition, we have a forward (dendrite to soma) transport term of 1 microns/sec. This converts to a rate of 0.1/sec, but applies only to the kf. So the total kf of the diffusion 'reaction' is 0.11 for D = 1 micron^2/sec, and kb is 0.01. If D=0.1 micron^2/sec then kf = 0.101 and kb = 0.001. In addition this model has all molecules buffered in the first and last compartments. This boundary conditions says that the molecules are not drained out of the first compartment, nor do they all pile up in the last one.
The stimulus file pkm_mapk22_transp_endbuf_D1e-13_Fig4CD which was used for the model to replicate Figure 4C and 4D from the paper.
   
This pathway is part of accession 83 and is completely specified in the file acc83.g.
There is no separate for just this pathway.
FormatFile
73 CaM
Pathway No. 688
 Ajay_Bhalla_
2007_ReacDiff2

Accession No. 83
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639645651657663669675681
695701706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 40-compartment reaction-diffusion-transport version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 40 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec In addition, we have a forward (dendrite to soma) transport term of 1 microns/sec. This converts to a rate of 0.1/sec, but applies only to the kf. So the total kf of the diffusion 'reaction' is 0.11 for D = 1 micron^2/sec, and kb is 0.01. If D=0.1 micron^2/sec then kf = 0.101 and kb = 0.001. In addition this model has all molecules buffered in the first and last compartments. This boundary conditions says that the molecules are not drained out of the first compartment, nor do they all pile up in the last one.
The stimulus file pkm_mapk22_transp_endbuf_D1e-13_Fig4CD which was used for the model to replicate Figure 4C and 4D from the paper.
   
This pathway is part of accession 83 and is completely specified in the file acc83.g.
There is no separate for just this pathway.
FormatFile
74 CaM
Pathway No. 695
 Ajay_Bhalla_
2007_ReacDiff2

Accession No. 83
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639645651657663669675681
688701706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 40-compartment reaction-diffusion-transport version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 40 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec In addition, we have a forward (dendrite to soma) transport term of 1 microns/sec. This converts to a rate of 0.1/sec, but applies only to the kf. So the total kf of the diffusion 'reaction' is 0.11 for D = 1 micron^2/sec, and kb is 0.01. If D=0.1 micron^2/sec then kf = 0.101 and kb = 0.001. In addition this model has all molecules buffered in the first and last compartments. This boundary conditions says that the molecules are not drained out of the first compartment, nor do they all pile up in the last one.
The stimulus file pkm_mapk22_transp_endbuf_D1e-13_Fig4CD which was used for the model to replicate Figure 4C and 4D from the paper.
   
This pathway is part of accession 83 and is completely specified in the file acc83.g.
There is no separate for just this pathway.
FormatFile
75 CaM
Pathway No. 701
 Ajay_Bhalla_
2007_ReacDiff2

Accession No. 83
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639645651657663669675681
688695706712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 40-compartment reaction-diffusion-transport version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 40 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec In addition, we have a forward (dendrite to soma) transport term of 1 microns/sec. This converts to a rate of 0.1/sec, but applies only to the kf. So the total kf of the diffusion 'reaction' is 0.11 for D = 1 micron^2/sec, and kb is 0.01. If D=0.1 micron^2/sec then kf = 0.101 and kb = 0.001. In addition this model has all molecules buffered in the first and last compartments. This boundary conditions says that the molecules are not drained out of the first compartment, nor do they all pile up in the last one.
The stimulus file pkm_mapk22_transp_endbuf_D1e-13_Fig4CD which was used for the model to replicate Figure 4C and 4D from the paper.
   
This pathway is part of accession 83 and is completely specified in the file acc83.g.
There is no separate for just this pathway.
FormatFile
76 CaM
Pathway No. 706
 Ajay_Bhalla_
2007_ReacDiff2

Accession No. 83
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639645651657663669675681
688695701712718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 40-compartment reaction-diffusion-transport version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 40 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec In addition, we have a forward (dendrite to soma) transport term of 1 microns/sec. This converts to a rate of 0.1/sec, but applies only to the kf. So the total kf of the diffusion 'reaction' is 0.11 for D = 1 micron^2/sec, and kb is 0.01. If D=0.1 micron^2/sec then kf = 0.101 and kb = 0.001. In addition this model has all molecules buffered in the first and last compartments. This boundary conditions says that the molecules are not drained out of the first compartment, nor do they all pile up in the last one.
The stimulus file pkm_mapk22_transp_endbuf_D1e-13_Fig4CD which was used for the model to replicate Figure 4C and 4D from the paper.
   
This pathway is part of accession 83 and is completely specified in the file acc83.g.
There is no separate for just this pathway.
FormatFile
77 CaM
Pathway No. 712
 Ajay_Bhalla_
2007_ReacDiff2

Accession No. 83
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639645651657663669675681
688695701706718724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 40-compartment reaction-diffusion-transport version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 40 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec In addition, we have a forward (dendrite to soma) transport term of 1 microns/sec. This converts to a rate of 0.1/sec, but applies only to the kf. So the total kf of the diffusion 'reaction' is 0.11 for D = 1 micron^2/sec, and kb is 0.01. If D=0.1 micron^2/sec then kf = 0.101 and kb = 0.001. In addition this model has all molecules buffered in the first and last compartments. This boundary conditions says that the molecules are not drained out of the first compartment, nor do they all pile up in the last one.
The stimulus file pkm_mapk22_transp_endbuf_D1e-13_Fig4CD which was used for the model to replicate Figure 4C and 4D from the paper.
   
This pathway is part of accession 83 and is completely specified in the file acc83.g.
There is no separate for just this pathway.
FormatFile
78 CaM
Pathway No. 718
 Ajay_Bhalla_
2007_ReacDiff2

Accession No. 83
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639645651657663669675681
688695701706712724730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 40-compartment reaction-diffusion-transport version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 40 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec In addition, we have a forward (dendrite to soma) transport term of 1 microns/sec. This converts to a rate of 0.1/sec, but applies only to the kf. So the total kf of the diffusion 'reaction' is 0.11 for D = 1 micron^2/sec, and kb is 0.01. If D=0.1 micron^2/sec then kf = 0.101 and kb = 0.001. In addition this model has all molecules buffered in the first and last compartments. This boundary conditions says that the molecules are not drained out of the first compartment, nor do they all pile up in the last one.
The stimulus file pkm_mapk22_transp_endbuf_D1e-13_Fig4CD which was used for the model to replicate Figure 4C and 4D from the paper.
   
This pathway is part of accession 83 and is completely specified in the file acc83.g.
There is no separate for just this pathway.
FormatFile
79 CaM
Pathway No. 724
 Ajay_Bhalla_
2007_ReacDiff2

Accession No. 83
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639645651657663669675681
688695701706712718730736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 40-compartment reaction-diffusion-transport version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 40 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec In addition, we have a forward (dendrite to soma) transport term of 1 microns/sec. This converts to a rate of 0.1/sec, but applies only to the kf. So the total kf of the diffusion 'reaction' is 0.11 for D = 1 micron^2/sec, and kb is 0.01. If D=0.1 micron^2/sec then kf = 0.101 and kb = 0.001. In addition this model has all molecules buffered in the first and last compartments. This boundary conditions says that the molecules are not drained out of the first compartment, nor do they all pile up in the last one.
The stimulus file pkm_mapk22_transp_endbuf_D1e-13_Fig4CD which was used for the model to replicate Figure 4C and 4D from the paper.
   
This pathway is part of accession 83 and is completely specified in the file acc83.g.
There is no separate for just this pathway.
FormatFile
80 CaM
Pathway No. 730
 Ajay_Bhalla_
2007_ReacDiff2

Accession No. 83
NetworkMolecule = 5
Enzyme   = 0
Reaction  = 4
Molecule = 1
Enzyme   = 0
Reaction  = 0
Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87/
2006-12-08 00:00:00
   Related Pathway: 
142781107122146160173203217236246259265273283323340358368373379386392
398405411418423428434440446452458464470476482488494500506512518524530537
543549555561568573579585591597603609615621627633639645651657663669675681
688695701706712718724736742748754760766772778784790796802808814820826832
838844850856862868874880886892898904910916924930936942948954961967973979
9859919971002100810141021102610321038104410501056106210681094
    This is a 40-compartment reaction-diffusion-transport version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 40 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec In addition, we have a forward (dendrite to soma) transport term of 1 microns/sec. This converts to a rate of 0.1/sec, but applies only to the kf. So the total kf of the diffusion 'reaction' is 0.11 for D = 1 micron^2/sec, and kb is 0.01. If D=0.1 micron^2/sec then kf = 0.101 and kb = 0.001. In addition this model has all molecules buffered in the first and last compartments. This boundary conditions says that the molecules are not drained out of the first compartment, nor do they all pile up in the last one.
The stimulus file pkm_mapk22_transp_endbuf_D1e-13_Fig4CD which was used for the model to replicate Figure 4C and 4D from the paper.
   
This pathway is part of accession 83 and is completely specified in the file acc83.g.
There is no separate for just this pathway.
FormatFile

 
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Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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