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Accession Type:
Network
AMPAR_CaMKII_
weak_coupling
Shared_Object_
AMPAR_CaMKII_
weak_coupling
CaMKII
CaM
 Molecule
 Reaction
PP1
PP2B
PP1_PSD
AMPAR
PKA
AC
AMPAR_memb
PP1_CaMKII_PSD
CaMKII_PSD

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Parameters for CaM (Pathway Number 283)

Pathway Layout

Pathway Basic Parameters

Pathway NameCaM
Pathway Entry Number 283
Accession Number 65
Accession Name AMPAR_CaMKII_weak_coupling
Species General Mammalian
Tissue Neuronal
CellCompartmentSynaptic Spine, Postsynaptic Density
Related Pathways 14, 27, 81, 107, 122, 146, 160, 173, 203, 217, 236, 246, 259, 265, 273, 323, 340, 358, 368, 373, 379, 386, 392, 398, 405, 411, 418, 423, 428, 434, 440, 446, 452, 458, 464, 470, 476, 482, 488, 494, 500, 506, 512, 518, 524, 530, 537, 543, 549, 555, 561, 568, 573, 579, 585, 591, 597, 603, 609, 615, 621, 627, 633, 639, 645, 651, 657, 663, 669, 675, 681, 688, 695, 701, 706, 712, 718, 724, 730, 736, 742, 748, 754, 760, 766, 772, 778, 784, 790, 796, 802, 808, 814, 820, 826, 832, 838, 844, 850, 856, 862, 868, 874, 880, 886, 892, 898, 904, 910, 916, 924, 930, 936, 942, 948, 954, 961, 967, 973, 979, 985, 991, 997, 1002, 1008, 1014, 1021, 1026, 1032, 1038, 1044, 1050, 1056, 1062, 1068, 1094
Notes  This is a model of weak coupling between the AMPAR traffikcing bistability, and the CaMKII autophosphorylation bistability. In this model, there are three stable states: Both off, AMPAR on, or both on. The fourth possible state: CaMKII on but AMPAR off, is not truly stable, since over the course of hours the AMPAR also turns on.

Statistics

Enzyme sites
8
0
9

Conversion format

This pathway is part of accession 65 and is completely specified in the file acc65.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc65.g   
MATLAB format    acc65.m   
SBML format    acc65.xml   


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Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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