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Reaction List for Accession fig4_synapse (Accession Number 3)

Entries are grouped according to Pathway Number and they are alternately color coded using  and  color.
Further ordering can be done to the table header.  indicates that ordering is done according to ascending or descending order.
Keq is calculated only for first order reactions.
Kd is calculated only for second order reactions. [nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules]
  Reaction
Name		Pathway Name / 
Pathway No.		KfKbKdtauReagents
1 Trimerize-GGq

Pathway No. 23		6
(uM^-1 s^-1)		0
(s^-1)		--  Substrate:
 G*GDP
 BetaGamma

 Products:
 G-GDP
2 remove_glu
  • Shared_Object_
    fig4_synapse
    Pathway No. 19
    		• 500
    (s^-1)    		1000
    (s^-1)    		Keq = 2(uM)0.001sec  Substrate:
     Glu

     Products:
     synapse
    3 Release-C2PKA

    Pathway No. 30    		60
    (s^-1)    		18
    (uM^-1 s^-1)    		Kd(cb) = 0.3(uM)-  Substrate:
     R2C-cAMP4

     Products:
     PKA-active
     R2-cAMP4
    4 Release-C1PKA

    Pathway No. 30    		60
    (s^-1)    		18
    (uM^-1 s^-1)    		Kd(cb) = 0.3(uM)-  Substrate:
     R2C2-cAMP4

     Products:
     PKA-active
     R2C-cAMP4
     The complex starts to dissociate and release catalytic subunit C. This has to be fast, as the activation of PKA by cAMP is also fast.
    5 
  • RecLigandBinding
    		• Gq

    Pathway No. 23    		16.8
    (uM^-1 s^-1)    		10
    (s^-1)    		Kd(bf) = 0.5952(uM)-  Substrate:
     mGluR
     Glu

     Products:
     Rec-Glu
    6 Rec-Glu-bind-GqGq

    Pathway No. 23    		0.006
    (uM^-1 s^-1)    		0.0001
    (s^-1)    		Kd(bf) = 0.0167(uM)-  Substrate:
     G-GDP
     Rec-Glu

     Products:
     Rec-Glu-Gq
    7 Rec-bind-GqGq

    Pathway No. 23    		0.6
    (uM^-1 s^-1)    		1
    (s^-1)    		Kd(bf) = 1.6667(uM)-  Substrate:
     G-GDP
     mGluR

     Products:
     Rec-Gq
    8 
  • Ras-intrinsic-GT
    Pase
    		• Ras

    Pathway No. 25    		0.0001
    (s^-1)    		0
    (s^-1)    		--  Substrate:
     GTP-Ras

     Products:
     GDP-Ras
    9 Ras-act-craf
  • Shared_Object_
    fig4_synapse
    Pathway No. 19
    		• 24
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 0.0208(uM)-  Substrate:
     craf-1*
     GTP-Ras

     Products:
     Raf-GTP-Ras*
    10 PLC-Gq-bind-CaPLCbeta

    Pathway No. 22    		30
    (uM^-1 s^-1)    		1
    (s^-1)    		Kd(bf) = 0.0333(uM)-  Substrate:
     Ca
     PLC-Gq

     Products:
     PLC-Ca-Gq
    11 PLC-bind-GqPLCbeta

    Pathway No. 22    		2.52
    (uM^-1 s^-1)    		1
    (s^-1)    		Kd(bf) = 0.3968(uM)-  Substrate:
     PLC
     G*GTP

     Products:
     PLC-Gq
    12 PLA2-Ca-actPLA2

    Pathway No. 21    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-  Substrate:
     PLA2-cytosolic
     Ca

     Products:
     PLA2-Ca*
    13 PLA2*-Ca-actPLA2

    Pathway No. 21    		6
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.0167(uM)-  Substrate:
     PLA2*
     Ca

     Products:
     PLA2*-Ca
    14 PKC-n-DAG-AAPKC

    Pathway No. 20    		0.018
    (uM^-1 s^-1)    		2
    (s^-1)    		Kd(bf) = 111.1111(uM)-  Substrate:
     PKC-DAG
     AA

     Products:
     PKC-DAG-AA
    15 PKC-n-DAGPKC

    Pathway No. 20    		0.0006
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 166.6667(uM)-  Substrate:
     PKC-cytosolic
     DAG

     Products:
     PKC-DAG
    16 PKC-DAG-to-membPKC

    Pathway No. 20    		1
    (s^-1)    		0.1
    (s^-1)    		Keq = 0.1(uM)0.909sec  Substrate:
     PKC-Ca-DAG

     Products:
     PKC-DAG-memb*
    17 PKC-Ca-to-membPKC

    Pathway No. 20    		1.2705
    (s^-1)    		3.5026
    (s^-1)    		Keq = 2.7569(uM)0.21sec  Substrate:
     PKC-Ca

     Products:
     PKC-Ca-memb*
    18 PKC-basal-actPKC

    Pathway No. 20    		1
    (s^-1)    		50
    (s^-1)    		Keq = 50(uM)0.02sec  Substrate:
     PKC-cytosolic

     Products:
     PKC-basal*
    19 
  • PKC-act-by-DAG-A
    A
    		• PKC

    Pathway No. 20    		2
    (s^-1)    		0.2
    (s^-1)    		Keq = 0.1(uM)0.455sec  Substrate:
     PKC-DAG-AA

     Products:
     PKC-DAG-AA*
    20 PKC-act-by-DAGPKC

    Pathway No. 20    		0.008
    (uM^-1 s^-1)    		8.6348
    (s^-1)    		Kd(bf) = 1079.377(uM)-  Substrate:
     DAG
     PKC-Ca

     Products:
     PKC-Ca-DAG
     
    Result: 1 - 20 of 70 rows are displayed Previous of 4  Next


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