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Molecule Parameter List for CaMKII***-PSD

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

CaMKII***-PSD participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	1	0	2	2	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
AMPAR_CaMKII_ weak_coupling	65	Network	Shared_Object_AMPAR_CaMKII_weak_coupling,  CaMKII,  CaM,   PP1,  PP2B,  PP1_PSD,   AMPAR,  PKA,  AC,   AMPAR_memb,  PP1_CaMKII_PSD,  CaMKII_PSD
This is a model of weak coupling between the AMPAR traffikcing bistability, and the CaMKII autophosphorylation bistability. In this model, there are three stable states: Both off, AMPAR on, or both on. The fourth possible state: CaMKII on but AMPAR off, is not truly stable, since over the course of hours the AMPAR also turns on.

CaMKII***-PSD acting as a Molecule in  AMPAR_CaMKII_weak_coupling Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
CaMKII***-PSD	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	0	0.01	No

CaMKII***-PSD acting as a Summed Molecule in  AMPAR_CaMKII_weak_coupling Network

Accession Name	Pathway Name	Target	Input
AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	tot-auto-PSD	CaMKII-thr286-PS D CaMKII***-PSD basal_CaMKII_ PSD

CaMKII***-PSD acting as a Substrate for an Enzyme in  AMPAR_CaMKII_weak_coupling Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PP1-active_ CaMKII_PSD  / Deph-thr305	AMPAR_CaMKII_ weak_coupling Accession No. : 65	PP1_CaMKII_PSD Pathway No. : 291	2.00001	0.2	4	explicit E-S complex	Substrate CaMKII***-PSD Product CaMKII-thr286-PS D
2	PP1-active_ CaMKII_PSD  / Deph-thr286c	AMPAR_CaMKII_ weak_coupling Accession No. : 65	PP1_CaMKII_PSD Pathway No. : 291	2.00001	0.2	4	explicit E-S complex	Substrate CaMKII***-PSD Product CaMKII-thr305-PS D

CaMKII***-PSD acting as a Product of an Enzyme in  AMPAR_CaMKII_weak_coupling Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	tot-CaM-CaMKII-P SD  / CaM-act-305-PSD	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	320	6	4	explicit E-S complex	Substrate CaMKII-thr286-PS D Product CaMKII***-PSD
2	tot-auto-PSD  / auton-305-PSD	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	500	6	4	explicit E-S complex	Substrate CaMKII-thr286-PS D Product CaMKII***-PSD