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Molecule Parameter List for tot-CaM-CaMKII-PSD

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
tot-CaM-CaMKII-PSD participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1130000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • AMPAR_CaMKII_
    weak_coupling
  • 65Network
    Shared_Object_AMPAR_CaMKII_weak_coupling CaMKII CaM 
    PP1 PP2B PP1_PSD 
    AMPAR PKA AC 
    AMPAR_memb PP1_CaMKII_PSD CaMKII_PSD 
    This is a model of weak coupling between the AMPAR traffikcing bistability, and the CaMKII autophosphorylation bistability. In this model, there are three stable states: Both off, AMPAR on, or both on. The fourth possible state: CaMKII on but AMPAR off, is not truly stable, since over the course of hours the AMPAR also turns on.

    tot-CaM-CaMKII-PSD acting as a Molecule in  
    AMPAR_CaMKII_weak_coupling Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    tot-CaM-CaMKII-PSD
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • CaMKII_PSD
    Pathway No. : 292
    00.01No

    tot-CaM-CaMKII-PSD acting as a Summed Molecule in  
    AMPAR_CaMKII_weak_coupling Network
    Accession NamePathway NameTargetInput
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • CaMKII_PSD
    Pathway No. : 292
    tot-CaM-CaMKII-PSD
  • CaMKII-thr286-Ca
    M-PSD

    CaMKII-CaM-PSD

  • tot-CaM-CaMKII-PSD acting as an Enzyme in  
    AMPAR_CaMKII_weak_coupling Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1
  • tot-CaM-CaMKII-P
    SD
     /
    CaM-act-305-PSD
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • CaMKII_PSD
    Pathway No. : 292
    32064explicit E-S complexSubstrate
  • CaMKII-thr286-PS
    D


    Product
    CaMKII***-PSD
  • 2
  • tot-CaM-CaMKII-P
    SD
     /
    CaM-act-286-PSD
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • CaMKII_PSD
    Pathway No. : 292
    319.9960.54explicit E-S complexSubstrate
    CaMKII-CaM-PSD

    Product
  • CaMKII-thr286-Ca
    M-PSD

  • 3
  • tot-CaM-CaMKII-P
    SD
     /
    CaM_act_autoph
  • AMPAR_CaMKII_
    weak_coupling

    Accession No. : 65
  • CaMKII_PSD
    Pathway No. : 292
    320.00224explicit E-S complexSubstrate
    CaMKII-PSD

    Product
  • CaMKII-thr286-PS
    D




  • Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.