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Molecule Parameter List for tot-CaM-CaMKII-PSD

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
tot-CaM-CaMKII-PSD participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1130000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • AMPAR_CaMKII_
    weak_coupling
    		• 65Network
    Shared_Object_AMPAR_CaMKII_weak_coupling,  CaMKII,  CaM,  
    PP1,  PP2B,  PP1_PSD,  
    AMPAR,  PKA,  AC,  
    AMPAR_memb,  PP1_CaMKII_PSD,  CaMKII_PSD 
    This is a model of weak coupling between the AMPAR traffikcing bistability, and the CaMKII autophosphorylation bistability. In this model, there are three stable states: Both off, AMPAR on, or both on. The fourth possible state: CaMKII on but AMPAR off, is not truly stable, since over the course of hours the AMPAR also turns on.

    tot-CaM-CaMKII-PSD acting as a Molecule in      AMPAR_CaMKII_weak_coupling Network
    NameAccession NamePathway NameInitial Conc.
    (uM)    		Volume
    (fL)    		Buffered
    tot-CaM-CaMKII-PSD
  • AMPAR_CaMKII_
    weak_coupling
    Accession No. : 65
    		• CaMKII_PSD
    Pathway No. : 292    		00.01No

    tot-CaM-CaMKII-PSD acting as a Summed Molecule in      AMPAR_CaMKII_weak_coupling Network
    Accession NamePathway NameTargetInput
  • AMPAR_CaMKII_
    weak_coupling
    Accession No. : 65
    		• CaMKII_PSD
    Pathway No. : 292    		tot-CaM-CaMKII-PSD
  • CaMKII-thr286-Ca
    M-PSD
    CaMKII-CaM-PSD

    • tot-CaM-CaMKII-PSD acting as an Enzyme in      AMPAR_CaMKII_weak_coupling Network
     Enzyme Molecule /
    Enzyme Activity    		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1
  • tot-CaM-CaMKII-P
    SD     /
    CaM-act-305-PSD
  • AMPAR_CaMKII_
    weak_coupling
    Accession No. : 65
    		• CaMKII_PSD
    Pathway No. : 292    		32064explicit E-S complexSubstrate
  • CaMKII-thr286-PS
    D

    Product
    CaMKII***-PSD
    • 2
  • tot-CaM-CaMKII-P
    SD     /
    CaM-act-286-PSD
  • AMPAR_CaMKII_
    weak_coupling
    Accession No. : 65
    		• CaMKII_PSD
    Pathway No. : 292    		319.9960.54explicit E-S complexSubstrate
    CaMKII-CaM-PSD

    Product
  • CaMKII-thr286-Ca
    M-PSD
    • 3
  • tot-CaM-CaMKII-P
    SD     /
    CaM_act_autoph
  • AMPAR_CaMKII_
    weak_coupling
    Accession No. : 65
    		• CaMKII_PSD
    Pathway No. : 292    		320.00224explicit E-S complexSubstrate
    CaMKII-PSD

    Product
  • CaMKII-thr286-PS
    D


    • Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.