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| PP1_CaMKII_PSD |
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Accession information for AMPAR_CaMKII_weak_coupling (Accession Number 65)
Reaction Scheme
Accession Basic Parameters
Name | AMPAR_CaMKII_weak_coupling |
Accession Type | Network |
Transcriber | Upinder S. Bhalla, NCBS |
Developer | Arnold Hayer and Upinder S. Bhalla, NCBS |
Entry Date (YYYY-MM-DD) | 2005-07-21 00:00:00 |
Species | General Mammalian |
Tissue | Neuronal |
Cell Compartment | Synaptic Spine, Postsynaptic Density |
Source | Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication ) |
Methodology | Quantitative match to experiments, Qualitative |
Model Implementation | Exact GENESIS implementation |
Model Validation | Replicates original data , Approximates original data |
Notes | This is a model of weak coupling between the AMPAR traffikcing bistability, and the CaMKII autophosphorylation bistability. In this model, there are three stable states: Both off, AMPAR on, or both on. The fourth possible state: CaMKII on but AMPAR off, is not truly stable, since over the course of hours the AMPAR also turns on. |
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| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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