Accession Name | Accession No. | Accession Type | Pathway Link |
Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 | 81 | Network | Shared_Object_Ajay_bhalla_2007_ReacDiff1_1e-12, PKC, MAPK, Ras, CaM, PKM, chain, kinetics, PKC, MAPK, Ras, CaM, PKM, kinetics[1], PKC, MAPK, Ras, CaM, PKM, kinetics[2], PKC, MAPK, Ras, CaM, PKM, kinetics[3], PKC, MAPK, MAPK, Ras, CaM, PKM, kinetics[4], PKC, MAPK, Ras, CaM, PKM, kinetics[5], PKC, MAPK, Ras, kinetics[6], CaM, PKM, PKC, MAPK, Ras, CaM, PKM, kinetics[7], PKC, Ras, CaM, PKM, kinetics[8], PKC, MAPK, Ras, CaM, PKM, kinetics[9], PKC, MAPK, Ras, CaM, PKM, kinetics[10], PKC, MAPK, Ras, CaM, PKM, kinetics[11], PKC, MAPK, Ras, CaM, PKM, kinetics[12], PKC, MAPK, Ras, CaM, PKM, kinetics[13], PKC, MAPK, Ras, CaM, PKM, kinetics[14], PKC, MAPK, Ras, CaM, PKM, kinetics[15], PKC, MAPK, Ras, CaM, PKM, kinetics[16], PKC, MAPK, Ras, CaM, PKM, kinetics[17], PKC, MAPK, Ras, CaM, PKM, kinetics[18], PKC, MAPK, Ras, CaM, PKM, kinetics[19], PKC, MAPK, Ras, CaM, PKM, kinetics[20], PKC, MAPK, Ras, CaM, PKM, kinetics[21], PKC, MAPK, Ras, CaM, PKM, kinetics[22], PKC, MAPK, Ras, CaM, PKM, kinetics[23], PKC, MAPK, Ras, CaM, PKM |
This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-12_Fig4A which was used for the model to replicate Figure 4A from the paper.
This stimulus file pkm_mapk22_diff_1e-12_Fig4G which was used for the model to replicate Figure 4G from the paper |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
1 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
2 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 376 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
3 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
4 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
5 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 383 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
6 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
7 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 401 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
8 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 389 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
9 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
10 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 395 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
11 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
12 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 426 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
13 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
14 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 408 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
15 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
16 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 414 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
17 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
18 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 420 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
19 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
20 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 473 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
21 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
22 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 431 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
23 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
24 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 437 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
25 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
26 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 443 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
27 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
28 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 449 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
29 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
30 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 455 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
31 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
32 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 461 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
33 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
34 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 467 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
35 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
36 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 479 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
37 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
38 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 485 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
39 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
40 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 491 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
41 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
42 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 497 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
43 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
44 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 503 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
45 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
46 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 509 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
47 | diff | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | Shared_Object_ Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Pathway No. : 375 | 0.01 (s^-1) | 0.01 (s^-1) | Keq = 1(uM) | 50sec | Substrate PKC-Ca
Product PKC-Ca
|
48 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 515 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |
49 | PKC-act-by-Ca | Ajay_bhalla_ 2007_ReacDiff1_ 1e-12 Accession No. : 81 | PKC Pathway No. : 521 | 0.6 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.8333(uM) | - | Substrate Ca PKC-cytosolic
Product PKC-Ca
|
| Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5 |