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Molecule Parameter List for AA

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

AA participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	25	0	0	0	125	124	24

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Ajay_Bhalla_ 2007_ReacDiff3	84	Network	Shared_Object_Ajay_Bhalla_2007_ReacDiff3, PKC, PLA2, MAPK, PLA2, Ras, CaM, chain, kinetics, PKC, MAPK, Ras, CaM, kinetics[1], PKC, PLA2, MAPK, Ras, CaM, kinetics[2], PKC, PLA2, MAPK, Ras, CaM, kinetics[3], PKC, PLA2, MAPK, Ras, CaM, kinetics[4], PKC, PLA2, MAPK, Ras, CaM, kinetics[5], PKC, PLA2, MAPK, Ras, MAPK, CaM, kinetics[6], PKC, PLA2, MAPK, Ras, CaM, kinetics[7], PKC, PLA2, MAPK, Ras, CaM, PKC, kinetics[8], PLA2, MAPK, Ras, CaM, kinetics[9], PKC, PLA2, MAPK, Ras, CaM, kinetics[10], PKC, PLA2, MAPK, Ras, CaM, kinetics[11], PKC, PLA2, MAPK, Ras, CaM, kinetics[12], PKC, PLA2, Ras, CaM, kinetics[13], PKC, PLA2, MAPK, Ras, CaM, kinetics[14], PKC, PLA2, MAPK, Ras, CaM, kinetics[15], PKC, PLA2, MAPK, Ras, kinetics[16], CaM, PKC, PLA2, MAPK, Ras, CaM, kinetics[17], PKC, PLA2, MAPK, Ras, CaM, kinetics[18], PKC, PLA2, MAPK, Ras, CaM, kinetics[19], PKC, PLA2, MAPK, Ras, CaM, kinetics[20], PKC, PLA2, MAPK, Ras, CaM, kinetics[21], PKC, PLA2, MAPK, Ras, CaM, kinetics[22], PKC, PLA2, MAPK, Ras, CaM, kinetics[23], PKC, PLA2, MAPK, Ras, CaM
This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_bistable model. The original single-compartment model is repeated 25 times. In addition, a subset (33 out of 50) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. Here D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) so the kf and kb of this reaction for these 10 micron compartments are both 0.001/sec. The basal calcium level in this model is held at 95 nM which is rather close to threshold for the flip to the active state. This is necessary to sustain active propagation of activation. The stimulus file bis6-propgn_D1e-13_FigEF which was used for the model to replicate Figure 4E and 4F from the paper.

AA acting as a Molecule in Ajay_Bhalla_2007_ReacDiff3 Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics Pathway No. : 926	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[1] Pathway No. : 931	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[2] Pathway No. : 937	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[3] Pathway No. : 943	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[4] Pathway No. : 949	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[5] Pathway No. : 955	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[6] Pathway No. : 962	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[7] Pathway No. : 968	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[8] Pathway No. : 975	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[9] Pathway No. : 980	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[10] Pathway No. : 986	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[11] Pathway No. : 992	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[12] Pathway No. : 998	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[13] Pathway No. : 1003	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[14] Pathway No. : 1009	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[15] Pathway No. : 1015	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[16] Pathway No. : 1020	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[17] Pathway No. : 1027	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[18] Pathway No. : 1033	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[19] Pathway No. : 1039	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[20] Pathway No. : 1045	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[21] Pathway No. : 1051	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[22] Pathway No. : 1057	0	125.7	No
AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	kinetics[23] Pathway No. : 1063	0	125.7	No

AA acting as a Product of an Enzyme in Ajay_Bhalla_2007_ReacDiff3 Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 920	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
2	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 920	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
3	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 920	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
4	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 920	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
5	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 920	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
6	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 922	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
7	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 922	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
8	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 922	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
9	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 922	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
10	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 922	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
11	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 933	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
12	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 933	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
13	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 933	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
14	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 933	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
15	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 933	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
16	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 939	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
17	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 939	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
18	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 939	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
19	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 939	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
20	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 939	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
21	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 945	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
22	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 945	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
23	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 945	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
24	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 945	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
25	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 945	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
26	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 951	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
27	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 951	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
28	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 951	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
29	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 951	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
30	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 951	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
31	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 957	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
32	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 957	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
33	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 957	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
34	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 957	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
35	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 957	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
36	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 964	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
37	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 964	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
38	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 964	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
39	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 964	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
40	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 964	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
41	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 970	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
42	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 970	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
43	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 970	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
44	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 970	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
45	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 970	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
46	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 976	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
47	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 976	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
48	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 976	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
49	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 976	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
50	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 976	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
51	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 982	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
52	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 982	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
53	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 982	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
54	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 982	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
55	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 982	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
56	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 988	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
57	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 988	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
58	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 988	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
59	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 988	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
60	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 988	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
61	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 994	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
62	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 994	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
63	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 994	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
64	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 994	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
65	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 994	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
66	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1000	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
67	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1000	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
68	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1000	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
69	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1000	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
70	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1000	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
71	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1005	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
72	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1005	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
73	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1005	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
74	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1005	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
75	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1005	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
76	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1011	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
77	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1011	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
78	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1011	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
79	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1011	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
80	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1011	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
81	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1017	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
82	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1017	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
83	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1017	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
84	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1017	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
85	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1017	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
86	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1023	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
87	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1023	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
88	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1023	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
89	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1023	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
90	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1023	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
91	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1029	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
92	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1029	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
93	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1029	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
94	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1029	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
95	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1029	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
96	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1035	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
97	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1035	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
98	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1035	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
99	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1035	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
100	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1035	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
101	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1041	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
102	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1041	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
103	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1041	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
104	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1041	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
105	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1041	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
106	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1047	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
107	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1047	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
108	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1047	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
109	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1047	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
110	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1047	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
111	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1053	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
112	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1053	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
113	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1053	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
114	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1053	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
115	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1053	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
116	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1059	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
117	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1059	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
118	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1059	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
119	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1059	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
120	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1059	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*
121	PLA2-Ca* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1065	19.9994	5.4	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct22 12 x oct 24, set k2 = 4 k3*
122	PIP2-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1065	19.9998	11.04	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X further raise oct 24 to allow for correct conc of enzyme
123	PIP2-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1065	20	36	4	explicit E-S complex	Substrate APC Product AA
	10 x raise oct 22 12 x and rescale for k2 = 4 * k3 convention oct 24 Increase further to get the match to expt, which was spoilt due to large accumulation of PLA2 in the enzyme complexed forms. Lets raise k3, leaving the others at k1 = 1.5e-5 and k2 = 144 since they are large already.
124	DAG-Ca-PLA2* / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1065	20	60	4	explicit E-S complex	Substrate APC Product AA
	10 X raise oct 22 12 X raise oct 24 + conversion to k2 =4 k3*
125	PLA2*-Ca / kenz	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1065	20	120	4	explicit E-S complex	Substrate APC Product AA
	This form should be 3 to 6 times as fast as the Ca-only form. I have scaled by 4x which seems to give a 5x rise. 10x raise Oct 22 12 x oct 24, changed k2 = 4 k3*

AA acting as a Substrate in a reaction in Ajay_Bhalla_2007_ReacDiff3 Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
2	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
3	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
4	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
5	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 920	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
6	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
7	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
8	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
9	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
10	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 922	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
11	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
12	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
13	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
14	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
15	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 933	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
16	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
17	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
18	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
19	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
20	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 939	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
21	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
22	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
23	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
24	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
25	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 945	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
26	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
27	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
28	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
29	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
30	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 951	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
31	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
32	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
33	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
34	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
35	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 957	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
36	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
37	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
38	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
39	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
40	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 964	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
41	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
42	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
43	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
44	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
45	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 970	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
46	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
47	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
48	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
49	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
50	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 976	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
51	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
52	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
53	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
54	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
55	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 982	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
56	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
57	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
58	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
59	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
60	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 988	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
61	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
62	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
63	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
64	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
65	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 994	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
66	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
67	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
68	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
69	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
70	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1000	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
71	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
72	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
73	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
74	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
75	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1005	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
76	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
77	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
78	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
79	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
80	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1011	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
81	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
82	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
83	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
84	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
85	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1017	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
86	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
87	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
88	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
89	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
90	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1023	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
91	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
92	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
93	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
94	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
95	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1029	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
96	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
97	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
98	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
99	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
100	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1035	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
101	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
102	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
103	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
104	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
105	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1041	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
106	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
107	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
108	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
109	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
110	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1047	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
111	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
112	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
113	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
114	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
115	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1053	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
116	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
117	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
118	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
119	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
120	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1059	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17
121	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
122	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
123	PKC-n-DAG-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	0.018 (uM^-1 s^-1)	2 (s^-1)	Kd(bf) = 111.1111(uM)	-	Substrate AA PKC-DAG Product PKC-DAG-AA
	Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2.
124	Degrade-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PLA2 Pathway No. : 1065	0.4 (s^-1)	0 (s^-1)	-	-	Substrate AA Product APC
	I need to check if the AA degradation pathway really leads back to APC. Anyway, it is a convenient buffered pool to dump it back into. For the purposes of the full model we use a rate of degradation of 0.2/sec Raised decay to 0.4 : see PLA35.g notes for Feb17

AA acting as a Product in a reaction in Ajay_Bhalla_2007_ReacDiff3 Network

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
2	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
3	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
4	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
5	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
6	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
7	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
8	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
9	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
10	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
11	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
12	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
13	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
14	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
15	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
16	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
17	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
18	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
19	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
20	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
21	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
22	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
23	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA
24	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate AA Product AA

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